2I61
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![BU of 2i61 by Molmil](/molmil-images/mine/2i61) | Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ... | Authors: | Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D. | Deposit date: | 2006-08-27 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity. J.Mol.Biol., 366, 2007
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1SEG
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![BU of 1seg by Molmil](/molmil-images/mine/1seg) | Crystal structure of a toxin chimera between Lqh-alpha-IT from the scorpion Leiurus quinquestriatus hebraeus and AAH2 from Androctonus australis hector | Descriptor: | AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN, NITRATE ION, PROPANOIC ACID, ... | Authors: | Karbat, I, Frolow, F, Froy, O, Gilles, N, Cohen, L, Turkov, M, Gordon, D, Gurevitz, M. | Deposit date: | 2004-02-17 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Molecular basis of the high insecticidal potency of scorpion alpha-toxins. J.Biol.Chem., 279, 2004
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1BCG
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![BU of 1bcg by Molmil](/molmil-images/mine/1bcg) | SCORPION TOXIN BJXTR-IT | Descriptor: | TOXIN BJXTR-IT | Authors: | Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B. | Deposit date: | 1998-04-29 | Release date: | 1998-11-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels. Structure, 6, 1998
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1LQH
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![BU of 1lqh by Molmil](/molmil-images/mine/1lqh) | INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | INSECT TOXIN ALPHA | Authors: | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | Deposit date: | 1996-06-17 | Release date: | 1997-03-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity. Biochemistry, 36, 1997
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1LQI
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![BU of 1lqi by Molmil](/molmil-images/mine/1lqi) | INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 29 STRUCTURES | Descriptor: | INSECT TOXIN ALPHA | Authors: | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | Deposit date: | 1996-06-17 | Release date: | 1997-03-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity. Biochemistry, 36, 1997
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6ZOI
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![BU of 6zoi by Molmil](/molmil-images/mine/6zoi) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | Conknunitzin-C3 mutante | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-07-07 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | A lid blocking mechanism of a cone snail toxin revealed at the atomic level To Be Published
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2ATB
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![BU of 2atb by Molmil](/molmil-images/mine/2atb) | Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ... | Authors: | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | Deposit date: | 2005-08-24 | Release date: | 2006-09-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant To be Published
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2YEO
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![BU of 2yeo by Molmil](/molmil-images/mine/2yeo) | A39L mutation of scorpion toxin lqh-alpha-it | Descriptor: | 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ... | Authors: | Frolow, F, Kahn, R, Gurevitz, M. | Deposit date: | 2011-03-28 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels To be Published
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2ASC
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![BU of 2asc by Molmil](/molmil-images/mine/2asc) | Scorpion toxin LQH-alpha-IT | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | Authors: | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | Deposit date: | 2005-08-23 | Release date: | 2006-09-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant To be Published
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6Q61
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![BU of 6q61 by Molmil](/molmil-images/mine/6q61) | Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | Descriptor: | Kunitz-type conkunitzin-S1, SULFATE ION | Authors: | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | Deposit date: | 2018-12-10 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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6Q6C
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![BU of 6q6c by Molmil](/molmil-images/mine/6q6c) | Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | Descriptor: | 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... | Authors: | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | Deposit date: | 2018-12-10 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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6YHT
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![BU of 6yht by Molmil](/molmil-images/mine/6yht) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | CITRIC ACID, Conk-C1, SULFATE ION | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-03-31 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide. J.Mol.Biol., 433, 2021
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6YHY
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![BU of 6yhy by Molmil](/molmil-images/mine/6yhy) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | Conk-S1 | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-03-31 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide. J.Mol.Biol., 433, 2021
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