6ZOI
 
 | | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | | 分子名称: | Conknunitzin-C3 mutante | | 著者 | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | | 登録日 | 2020-07-07 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | A lid blocking mechanism of a cone snail toxin revealed at the atomic level
To Be Published
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2I61
 | | Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ... | | 著者 | Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D. | | 登録日 | 2006-08-27 | | 公開日 | 2006-12-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.
J.Mol.Biol., 366, 2007
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1LQH
 | | INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | INSECT TOXIN ALPHA | | 著者 | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | | 登録日 | 1996-06-17 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.
Biochemistry, 36, 1997
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1LQI
 | | INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 29 STRUCTURES | | 分子名称: | INSECT TOXIN ALPHA | | 著者 | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | | 登録日 | 1996-06-17 | | 公開日 | 1997-03-12 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.
Biochemistry, 36, 1997
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2YEO
 | | A39L mutation of scorpion toxin lqh-alpha-it | | 分子名称: | 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ... | | 著者 | Frolow, F, Kahn, R, Gurevitz, M. | | 登録日 | 2011-03-28 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
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1SEG
 | | Crystal structure of a toxin chimera between Lqh-alpha-IT from the scorpion Leiurus quinquestriatus hebraeus and AAH2 from Androctonus australis hector | | 分子名称: | AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN, NITRATE ION, PROPANOIC ACID, ... | | 著者 | Karbat, I, Frolow, F, Froy, O, Gilles, N, Cohen, L, Turkov, M, Gordon, D, Gurevitz, M. | | 登録日 | 2004-02-17 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular basis of the high insecticidal potency of scorpion alpha-toxins.
J.Biol.Chem., 279, 2004
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1BCG
 | | SCORPION TOXIN BJXTR-IT | | 分子名称: | TOXIN BJXTR-IT | | 著者 | Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B. | | 登録日 | 1998-04-29 | | 公開日 | 1998-11-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels.
Structure, 6, 1998
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6Q61
 | | Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | | 分子名称: | Kunitz-type conkunitzin-S1, SULFATE ION | | 著者 | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | | 登録日 | 2018-12-10 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6Q6C
 | | Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | | 分子名称: | 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... | | 著者 | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | | 登録日 | 2018-12-10 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2ATB
 | | Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ... | | 著者 | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | | 登録日 | 2005-08-24 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
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2ASC
 | | Scorpion toxin LQH-alpha-IT | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | | 著者 | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | | 登録日 | 2005-08-23 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
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6YHT
 | | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | | 分子名称: | CITRIC ACID, Conk-C1, SULFATE ION | | 著者 | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | | 登録日 | 2020-03-31 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
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6YHY
 | | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | | 分子名称: | Conk-S1 | | 著者 | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | | 登録日 | 2020-03-31 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
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