8C2Z
 
 | | Crystal structure of DYRK1B in complex with AZ191 | | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 1B, MANGANESE (II) ION, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | | 登録日 | 2022-12-23 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structural perspective on the design of selective DYRK1B inhibitors
To Be Published
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8C3Q
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8C3R
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7Z1G
 | | Crystal structure of nonphosphorylated (Tyr216) GSK3b in complex with CX-4945 | | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Glycogen synthase kinase-3 beta, IMIDAZOLE, ... | | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | | 登録日 | 2022-02-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of nonphosphorylated (Tyr216) GSK3b kinase in complex with CX-4945
To Be Published
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7Z1F
 | | Crystal structure of GSK3b in complex with CX-4945 | | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Glycogen synthase kinase-3 beta, IMIDAZOLE, ... | | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | | 登録日 | 2022-02-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of phosphorylated (Tyr216) GSK3b kinase in complex with CX-4945
To Be Published
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8C3G
 | | Crystal structure of DYRK1A in complex with AZ191 | | 分子名称: | 1,2-ETHANEDIOL, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine, ... | | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | | 登録日 | 2022-12-23 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural perspective on the design of selective DYRK1B inhibitors
To Be Published
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8QJI
 | | Crystal structure of GSK3b in complex with N-(4-(5-(1,2,4-oxadiazol-3-yl)thiophen-2-yl)pyridin-2-yl)cyclopropanecarboxamide inhibitor (TW362) | | 分子名称: | Glycogen synthase kinase-3 beta, N-[4-[5-(1,2,4-oxadiazol-3-yl)thiophen-2-yl]pyridin-2-yl]cyclopropanecarboxamide | | 著者 | Slugocka, E.A, Grygier, P, Wichur, T, Czarna, A, Wieckowska, A. | | 登録日 | 2023-09-13 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Exploring Novel GSK-3 beta Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation.
Acs Chem Neurosci, 15, 2024
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7Z5N
 | | Crystal structure of DYRK1A in complex with CX-4945 | | 分子名称: | 1,2-ETHANEDIOL, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Pustelny, K, Grygier, P, Golik, P, Dubin, G, Czarna, A. | | 登録日 | 2022-03-09 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Crystal structure DYRK1A in complex with CX-4945
To Be Published
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