2V10
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![BU of 2v10 by Molmil](/molmil-images/mine/2v10) | Crystal Structure of Renin with Inhibitor 9 | Descriptor: | (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE, RENIN | Authors: | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | Deposit date: | 2007-05-21 | Release date: | 2007-07-03 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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3MAF
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![BU of 3maf by Molmil](/molmil-images/mine/3maf) | Crystal structure of StSPL (asymmetric form) | Descriptor: | CHLORIDE ION, PHOSPHATE ION, sphingosine-1-phosphate lyase | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-23 | Release date: | 2010-08-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.971 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
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3MAD
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![BU of 3mad by Molmil](/molmil-images/mine/3mad) | |
3MBB
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![BU of 3mbb by Molmil](/molmil-images/mine/3mbb) | Crystal structure of StSPL - apo form, after treatment with semicarbazide | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ... | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-25 | Release date: | 2010-08-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
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3MC6
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![BU of 3mc6 by Molmil](/molmil-images/mine/3mc6) | Crystal structure of ScDPL1 | Descriptor: | PHOSPHATE ION, Sphingosine-1-phosphate lyase | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-27 | Release date: | 2010-08-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
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1J0X
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![BU of 1j0x by Molmil](/molmil-images/mine/1j0x) | Crystal structure of the rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase | Authors: | Cowan-Jacob, S.W, Kaufmann, M, Anselmo, A.N, Stark, W, Grutter, M.G. | Deposit date: | 2002-11-25 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase. Acta Crystallogr.,Sect.D, 59, 2003
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1JPF
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![BU of 1jpf by Molmil](/molmil-images/mine/1jpf) | Crystal Structure Of The LCMV Peptidic Epitope Gp276 In Complex With The Murine Class I Mhc Molecule H-2Db | Descriptor: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | Authors: | Ciatto, C, Tissot, A.C, Tschopp, M, Capitani, G, Pecorari, F, Pluckthun, A, Grutter, M.G. | Deposit date: | 2001-08-02 | Release date: | 2001-10-24 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides. J.Mol.Biol., 312, 2001
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1JPG
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![BU of 1jpg by Molmil](/molmil-images/mine/1jpg) | Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db | Descriptor: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | Authors: | Ciatto, C, Tissot, A.C, Tschopp, M, Capitani, G, Pecorari, F, Pluckthun, A, Grutter, M.G. | Deposit date: | 2001-08-02 | Release date: | 2001-10-24 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides. J.Mol.Biol., 312, 2001
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1M4N
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![BU of 1m4n by Molmil](/molmil-images/mine/1m4n) | CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH [2-(AMINO-OXY)ETHYL](5'-DEOXYADENOSIN-5'-YL)(METHYL)SULFONIUM | Descriptor: | (2-AMINOOXY-ETHYL)-[5-(6-AMINO-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]-METHYL-SULFONIUM, 1-aminocyclopropane-1-carboxylate synthase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Capitani, G, Eliot, A.C, Gut, H, Khomutov, R.M, Kirsch, J.F, Grutter, M.G. | Deposit date: | 2002-07-03 | Release date: | 2003-04-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding. BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003
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2XEH
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![BU of 2xeh by Molmil](/molmil-images/mine/2xeh) | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module. | Descriptor: | NI3C MUT6, SULFATE ION | Authors: | Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M. | Deposit date: | 2010-05-14 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module. J.Mol.Biol., 404, 2010
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4DBA
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![BU of 4dba by Molmil](/molmil-images/mine/4dba) | Designed Armadillo repeat protein (YIIM3AII) | Descriptor: | Designed Armadillo repeat protein, YIIM3AII, GLYCEROL | Authors: | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | Deposit date: | 2012-01-13 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
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2XEE
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![BU of 2xee by Molmil](/molmil-images/mine/2xee) | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module. | Descriptor: | NI3C DARPIN MUTANT5 | Authors: | Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M. | Deposit date: | 2010-05-14 | Release date: | 2010-08-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module. J.Mol.Biol., 404, 2010
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2XEN
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![BU of 2xen by Molmil](/molmil-images/mine/2xen) | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module. | Descriptor: | 1,2-ETHANEDIOL, METHANOL, NI1C MUT4, ... | Authors: | Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M. | Deposit date: | 2010-05-17 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module. J.Mol.Biol., 404, 2010
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1ZE3
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![BU of 1ze3 by Molmil](/molmil-images/mine/1ze3) | Crystal Structure of the Ternary Complex of FIMD (N-Terminal Domain) with FIMC and the Pilin Domain of FIMH | Descriptor: | 1,2-ETHANEDIOL, Chaperone protein fimC, FimH protein, ... | Authors: | Nishiyama, M, Horst, R, Eidam, O, Herrmann, T, Ignatov, O, Vetsch, M, Bettendorff, P, Jelesarov, I, Grutter, M.G, Wuthrich, K, Glockshuber, R, Capitani, G. | Deposit date: | 2005-04-17 | Release date: | 2005-06-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural basis of chaperone-subunit complex recognition by the type 1 pilus assembly platform FimD. Embo J., 24, 2005
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1KSO
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![BU of 1kso by Molmil](/molmil-images/mine/1kso) | CRYSTAL STRUCTURE OF APO S100A3 | Descriptor: | S100 CALCIUM-BINDING PROTEIN A3 | Authors: | Mittl, P.R, Fritz, G, Sargent, D.F, Richmond, T.J, Heizmann, C.W, Grutter, M.G. | Deposit date: | 2002-01-14 | Release date: | 2002-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Metal-free MIRAS phasing: structure of apo-S100A3. Acta Crystallogr.,Sect.D, 58, 2002
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4DB8
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![BU of 4db8 by Molmil](/molmil-images/mine/4db8) | Designed Armadillo-repeat Protein | Descriptor: | Armadillo-repeat Protein, MAGNESIUM ION | Authors: | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | Deposit date: | 2012-01-13 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
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4DB6
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![BU of 4db6 by Molmil](/molmil-images/mine/4db6) | Designed Armadillo repeat protein (YIIIM3AII) | Descriptor: | Armadillo repeat protein | Authors: | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | Deposit date: | 2012-01-13 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
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1ZDV
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![BU of 1zdv by Molmil](/molmil-images/mine/1zdv) | Solution Structure of the type 1 pilus assembly platform FimD(25-139) | Descriptor: | Outer membrane usher protein fimD | Authors: | Nishiyama, M, Horst, R, Herrmann, T, Vetsch, M, Bettendorff, P, Ignatov, O, Grutter, M, Wuthrich, K, Glockshuber, R, Capitani, G. | Deposit date: | 2005-04-15 | Release date: | 2005-06-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis of chaperone-subunit complex recognition by the type 1 pilus assembly platform FimD. Embo J., 24, 2005
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1ZDX
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![BU of 1zdx by Molmil](/molmil-images/mine/1zdx) | Solution Structure of the type 1 pilus assembly platform FimD(25-125) | Descriptor: | Outer membrane usher protein fimD | Authors: | Nishiyama, M, Horst, R, Herrmann, T, Vetsch, M, Bettendorff, P, Ignatov, O, Grutter, M, Wuthrich, K, Glockshuber, R, Capitani, G. | Deposit date: | 2005-04-15 | Release date: | 2005-06-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis of chaperone-subunit complex recognition by the type 1 pilus assembly platform FimD. Embo J., 24, 2005
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2XZD
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![BU of 2xzd by Molmil](/molmil-images/mine/2xzd) | Caspase-3 in Complex with an Inhibitory DARPin-3.4 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CASPASE-3, ... | Authors: | Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G. | Deposit date: | 2010-11-24 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Specific Inhibition of Caspase-3 by a Competitive Darpin: Molecular Mimicry between Native and Designed Inhibitors. Structure, 21, 2013
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1KKC
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![BU of 1kkc by Molmil](/molmil-images/mine/1kkc) | Crystal structure of Aspergillus fumigatus MnSOD | Descriptor: | MANGANESE (II) ION, Manganese Superoxide Dismutase | Authors: | Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R. | Deposit date: | 2001-12-07 | Release date: | 2001-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. J.Immunol., 168, 2002
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2XZT
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![BU of 2xzt by Molmil](/molmil-images/mine/2xzt) | Caspase-3 in Complex with DARPin-3.4_I78S | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CASPASE-3, DARPIN-3.4_I78S | Authors: | Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G. | Deposit date: | 2010-11-29 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Caspase-3 in Complex with Darpin-3.4_I78S To be Published
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2Y0B
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![BU of 2y0b by Molmil](/molmil-images/mine/2y0b) | Caspase-3 in Complex with an Inhibitory DARPin-3.4_S76R | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CASPASE-3, ... | Authors: | Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G. | Deposit date: | 2010-12-01 | Release date: | 2011-12-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Specific Inhibition of Caspase-3 by a Competitive Darpin: Molecular Mimicry between Native and Designed Inhibitors. Structure, 21, 2013
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2Y1L
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![BU of 2y1l by Molmil](/molmil-images/mine/2y1l) | Caspase-8 in Complex with DARPin-8.4 | Descriptor: | 1,2-ETHANEDIOL, AC-IETD-CHO, CASPASE-8, ... | Authors: | Barandun, J, Schroeder, T, Mittl, P.R.E, Grutter, M.G. | Deposit date: | 2010-12-08 | Release date: | 2011-12-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Caspase-8 in Complex with Darpin-8.4 To be Published
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4DB9
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![BU of 4db9 by Molmil](/molmil-images/mine/4db9) | Designed Armadillo repeat protein (YIIIM3AIII) | Descriptor: | Armadillo repeat protein, YIIIM3AIII | Authors: | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | Deposit date: | 2012-01-13 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
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