7A2B
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q207D | 分子名称: | MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Bischoff, D, Hermann, J, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-08-17 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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6MEM
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6B5B
| Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome | 分子名称: | Baculoviral IAP repeat-containing protein 1e, Flagellin, NLR family CARD domain-containing protein 4 | 著者 | Tenthorey, J.L, Haloupek, N, Lopez-Blanco, J.R, Grob, P, Adamson, E, Hartenian, E, Lind, N.A, Bourgeois, N.M, Chacon, P, Nogales, E, Vance, R.E. | 登録日 | 2017-09-29 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science, 358, 2017
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3J0K
| Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | 著者 | Bernecky, C, Grob, P, Ebmeier, C.C, Nogales, E, Taatjes, D.J. | 登録日 | 2011-10-04 | 公開日 | 2011-10-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (36 Å) | 主引用文献 | Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. Plos Biol., 9, 2011
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6Y0Z
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126K | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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6Y10
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126H | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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1KV1
| p38 MAP Kinase in Complex with Inhibitor 1 | 分子名称: | 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, p38 MAP kinase | 著者 | Pargellis, C, Tong, L, Churchill, L, Cirillo, P.F, Gilmore, T, Graham, A.G, Grob, P.M, Hickey, E.R, Moss, N, Pav, S, Regan, J. | 登録日 | 2002-01-23 | 公開日 | 2002-03-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat.Struct.Biol., 9, 2002
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6Y1B
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant K32A_Q126K | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization. Biotechnol J, 15, 2020
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6Y0S
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant T102E | 分子名称: | MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization. Biotechnol J, 15, 2020
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1KV2
| Human p38 MAP Kinase in Complex with BIRB 796 | 分子名称: | 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, p38 MAP kinase | 著者 | Pargellis, C, Tong, L, Churchill, L, Cirillo, P.F, Gilmore, T, Graham, A.G, Grob, P.M, Hickey, E.R, Moss, N, Pav, S, Regan, J. | 登録日 | 2002-01-23 | 公開日 | 2002-03-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat.Struct.Biol., 9, 2002
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6Y15
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant T102E_Q126K | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization. Biotechnol J, 15, 2020
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6Y1C
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant D54F | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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8FIZ
| Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-18 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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8FIY
| Cryo-EM structure of E. coli RNA polymerase Elongation complex in the Transcription-Translation Complex (RNAP in an anti-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-17 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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8FIX
| Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-17 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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