6XZP
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | Descriptor: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-05 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6Y0C
| Influenza C virus polymerase in complex with human ANP32A - Subclass 2 | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ... | Authors: | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-07 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZD
| Influenza C virus polymerase complex without chicken ANP32A - Subclass 2 | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-04 | Release date: | 2020-12-23 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6XZQ
| Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | Deposit date: | 2020-02-05 | Release date: | 2020-11-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6FLB
| 3H5 Fab bound to EDIII of DenV 2 Xtal form 2 | Descriptor: | CHLORIDE ION, Domain III of Dengue virus 2, GLYCEROL, ... | Authors: | Flanagan, A, Renner, M, Grimes, J.M. | Deposit date: | 2018-01-25 | Release date: | 2018-10-24 | Last modified: | 2018-10-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus. Nat. Immunol., 19, 2018
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6FLC
| 2C8 Fab bound to EDIII of DenV 2 | Descriptor: | Domain III of Dengue virus 2, GLYCEROL, Heavy chain of 2C8 Fab, ... | Authors: | Flanagan, A, Renner, M, Grimes, J.M. | Deposit date: | 2018-01-25 | Release date: | 2018-10-24 | Last modified: | 2018-10-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus. Nat. Immunol., 19, 2018
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8R60
| 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-19 | Release date: | 2024-03-27 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II. J.Virol., 98, 2024
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8R65
| 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-20 | Release date: | 2024-03-27 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II. J.Virol., 98, 2024
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5CE3
| The Yersinia YopO - actin complex with MgADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Lee, W.L, Singaravelu, P, Grimes, J.M, Robinson, R.C. | Deposit date: | 2015-07-06 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | The Yersinia YopO - actin complex with MgADP To Be Published
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8P1J
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8P1L
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5DHV
| HIV-1 Rev NTD dimers with variable crossing angles | Descriptor: | Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, light chain, ... | Authors: | DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C. | Deposit date: | 2015-08-31 | Release date: | 2016-06-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly. Structure, 24, 2016
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5DHZ
| HIV-1 Rev NTD dimers with variable crossing angles | Descriptor: | Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, light chain, ... | Authors: | DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C. | Deposit date: | 2015-08-31 | Release date: | 2016-06-29 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly. Structure, 24, 2016
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5DHX
| HIV-1 Rev NTD dimers with variable crossing angles | Descriptor: | Anti-Rev Antibody Fab single-chain variable fragment, light chain,Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, ... | Authors: | DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C. | Deposit date: | 2015-08-31 | Release date: | 2016-06-22 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly. Structure, 24, 2016
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8P1K
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8P1M
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1W8X
| Structural analysis of PRD1 | Descriptor: | MAJOR CAPSID PROTEIN (PROTEIN P3), PROTEIN P16, PROTEIN P30, ... | Authors: | Abrescia, N.G.A, Cockburn, J.J.B, Grimes, J.M, Sutton, G.C, Diprose, J.M, Butcher, S.J, Fuller, S.D, San Martin, C, Burnett, R.M, Stuart, D.I, Bamford, D.H, Bamford, J.K.H. | Deposit date: | 2004-10-01 | Release date: | 2004-11-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Insights Into Assembly from Structural Analysis of Bacteriophage Prd1. Nature, 432, 2004
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5D98
| Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212 | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | Deposit date: | 2015-08-18 | Release date: | 2015-10-21 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus. Nature, 527, 2015
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2X7L
| Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV | Authors: | DiMattia, M.A, Watts, N.R, Stahl, S.J, Rader, C, Wingfield, P.T, Stuart, D.I, Steven, A.C, Grimes, J.M. | Deposit date: | 2010-03-01 | Release date: | 2010-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element. Proc.Natl.Acad.Sci.USA, 107, 2010
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5DHY
| HIV-1 Rev NTD dimers with variable crossing angles | Descriptor: | Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, light chain, ... | Authors: | DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C. | Deposit date: | 2015-08-31 | Release date: | 2016-06-22 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly. Structure, 24, 2016
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5D9A
| Influenza C Virus RNA-dependent RNA Polymerase - Space group P212121 | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | Authors: | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | Deposit date: | 2015-08-18 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus. Nature, 527, 2015
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8P1N
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1D4V
| Crystal structure of trail-DR5 complex | Descriptor: | DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND | Authors: | Mongkolsapaya, J, Grimes, J.M, Stuart, D.I, Jones, E.Y, Screaton, G.R. | Deposit date: | 1999-10-06 | Release date: | 1999-11-01 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation Nat.Struct.Biol., 6, 1999
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4S1K
| Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 100 K | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin | Authors: | Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun, 6, 2015
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4S1L
| Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 298 K | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, polyhedrin | Authors: | Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun, 6, 2015
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