2BTV
 
 | | ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | | Descriptor: | PROTEIN (VP3 CORE PROTEIN), PROTEIN (VP7 CORE PROTEIN) | | Authors: | Grimes, J.M, Burroughs, J.N, Gouet, P, Diprose, J.M, Malby, R, Zientras, S, Mertens, P.P.C, Stuart, D.I. | | Deposit date: | 1998-09-05 | | Release date: | 1998-09-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The atomic structure of the bluetongue virus core.
Nature, 395, 1998
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1HI8
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | | Descriptor: | MAGNESIUM ION, P2 PROTEIN | | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | Deposit date: | 2001-01-03 | | Release date: | 2001-03-27 | | Last modified: | 2019-09-18 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HHT
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | Deposit date: | 2000-12-28 | | Release date: | 2001-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HHS
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | Deposit date: | 2000-12-28 | | Release date: | 2001-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HI1
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | Deposit date: | 2001-01-01 | | Release date: | 2001-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HI0
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | Deposit date: | 2000-12-31 | | Release date: | 2001-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1UVJ
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA | | Descriptor: | 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | | Authors: | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2004-01-21 | | Release date: | 2004-02-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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3ZED
 | | X-ray structure of the birnavirus VP1-VP3 complex | | Descriptor: | CAPSID PROTEIN VP3, GLYCEROL, POTASSIUM ION, ... | | Authors: | Bahar, M.W, Sarin, L.P, Graham, S.C, Pang, J, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2012-12-04 | | Release date: | 2013-01-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a Vp1-Vp3 Complex Suggests How Birnaviruses Package the Vp1 Polymerase.
J.Virol., 87, 2013
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3ZN5
 | | VP16, a capsid protein of bacteriophage P23-77 (VP16-virus-derived) | | Descriptor: | CHLORIDE ION, VP16 | | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
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3ZMO
 | | VP16, a capsid protein of bacteriophage P23-77 (VP16-type-1) | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | | Deposit date: | 2013-02-11 | | Release date: | 2013-05-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
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3ZN6
 | | VP16-VP17 complex, a complex of the two major capsid proteins of bacteriophage P23-77 | | Descriptor: | CHLORIDE ION, SODIUM ION, VP16, ... | | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
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3ZN4
 | | VP16, a capsid protein of bacteriophage P23-77 (VP16-type-2) | | Descriptor: | CHLORIDE ION, CITRIC ACID, VP16 | | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
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4LP7
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6ZQU
 | | Cryo-EM structure of mature Dengue virus 2 at 3.1 angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | Authors: | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | Deposit date: | 2020-07-10 | | Release date: | 2021-01-20 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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8PX5
 | | Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe., solved at wavelength 2.75 A | | Descriptor: | Rpb7-binding protein seb1 | | Authors: | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Wittmann, S, Renner, M, Grimes, J.M, Wagner, A. | | Deposit date: | 2023-07-22 | | Release date: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
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6ZQI
 | | Cryo-EM structure of Spondweni virus prME | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | Authors: | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | Deposit date: | 2020-07-09 | | Release date: | 2021-01-20 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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8R1L
 | | Structure of avian H5N1 influenza A polymerase in complex with human ANP32B. | | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | Deposit date: | 2023-11-02 | | Release date: | 2024-05-08 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation.
Nat Commun, 15, 2024
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6S5V
 | | Crystal structure of the Cap-Midlink region of the H5N1 Influenza A virus polymerase in complex with a Cap-domain binding analogue | | Descriptor: | (1~{S},2~{S},3~{S},6~{R})-2-[[2-[5,7-bis(fluoranyl)-1~{H}-indol-3-yl]-5-fluoranyl-pyrimidin-4-yl]amino]-3,6-dimethyl-cyclohexane-1-carboxylic acid, GLYCEROL, POTASSIUM ION, ... | | Authors: | Keown, J.R, Fodor, E, Grimes, J.M. | | Deposit date: | 2019-07-02 | | Release date: | 2019-11-06 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
J.Med.Chem., 62, 2019
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8R1J
 | | Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. | | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | Deposit date: | 2023-11-02 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation.
Nat Commun, 15, 2024
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8BCK
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8BC5
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8BBT
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8BCL
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8BS7
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6RR7
 | | Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... | | Authors: | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | Deposit date: | 2019-05-17 | | Release date: | 2019-09-04 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
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