7T4Q
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
|
|
7T4R
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
|
|
7T4S
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ... | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | 登録日 | 2021-12-10 | 公開日 | 2022-03-23 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
|
|
6E1M
| Structure of AtTPC1(DDE) reconstituted in saposin A | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6E1P
| Structure of AtTPC1(DDE) in state 2 | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1 | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6E1N
| Structure of AtTPC1(DDE) in state 1 | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6E1K
| Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5I74
| X-ray structure of the ts3 human serotonin transporter complexed with Br-citalopram at the central site | 分子名称: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.395 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I71
| X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site | 分子名称: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I6X
| X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I73
| X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central and allosteric sites | 分子名称: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I6Z
| X-ray structure of the ts2 human serotonin transporter | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I66
| X-ray structure of the Fab fragment of 8B6, a murine monoclonal antibody specific for the human serotonin transporter | 分子名称: | 8B6 antibody, heavy chain, light chain | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.624 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
5I75
| X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site | 分子名称: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
|
|
3P4D
| Alternatingly modified 2'Fluoro RNA octamer f/rC4G4 | 分子名称: | 5'-R(*(CFZ)P*CP*(CFZ)P*CP*(GF2)P*GP*(GF2)P*G)-3' | 著者 | Pallan, P.S, Greene, E.M, Jicman, P.A, Pandey, R.K, Manoharan, M, Rozners, E, Egli, M. | 登録日 | 2010-10-06 | 公開日 | 2011-01-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res., 39, 2011
|
|
3P4C
| Alternatingly modified 2'Fluoro RNA octamer f/rA2U2-R32 | 分子名称: | 5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3', STRONTIUM ION | 著者 | Pallan, P.S, Greene, E.M, Jicman, P.A, Pandey, R.K, Manoharan, M, Rozners, E, Egli, M. | 登録日 | 2010-10-06 | 公開日 | 2011-01-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res., 39, 2011
|
|
3P4B
| Alternatingly modified 2'Fluoro RNA octamer f/rA2U2-P3 | 分子名称: | 5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3', BARIUM ION | 著者 | Pallan, P.S, Greene, E.M, Jicman, P.A, Pandey, R.K, Manoharan, M, Rozners, E, Egli, M. | 登録日 | 2010-10-06 | 公開日 | 2011-01-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res., 39, 2011
|
|
3P4A
| 2'Fluoro modified RNA octamer fA2U2 | 分子名称: | 2'Fluoro modified RNA 8-MER, MAGNESIUM ION, STRONTIUM ION | 著者 | Manoharan, M, Akinc, A, Pandey, R.K, Qin, J, Hadwiger, P, John, M, Mills, K, Charisse, K, Maier, M.A, Nechev, L, Greene, E.M, Pallan, P.S, Rozners, E, Rajeev, K.G, Egli, M. | 登録日 | 2010-10-06 | 公開日 | 2011-01-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res., 39, 2011
|
|