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PDB: 35 results
5G1P
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BU of 5g1p by Molmil
Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate
Descriptor: CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
Authors:Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
Deposit date:2016-03-29
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5G1N
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BU of 5g1n by Molmil
Aspartate transcarbamoylase domain of human CAD bound to PALA
Descriptor: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Authors:Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
Deposit date:2016-03-29
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5G1O
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BU of 5g1o by Molmil
Aspartate transcarbamoylase domain of human CAD in apo form
Descriptor: 1,2-ETHANEDIOL, CAD protein, GLYCEROL
Authors:Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
Deposit date:2016-03-29
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5NNQ
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BU of 5nnq by Molmil
Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
Descriptor: GLYCEROL, ctATC
Authors:Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
Deposit date:2017-04-10
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
5NNN
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BU of 5nnn by Molmil
Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like
Descriptor: GLYCEROL, ctATC
Authors:Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
Deposit date:2017-04-10
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
5NNL
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BU of 5nnl by Molmil
Inactive dihydroorotase-like domain of Chaetomium thermophilum CAD-like multifunctional protein
Descriptor: Inactive dihydroorotase-like domain
Authors:Ramon-Maiques, S, Moreno-Morcillo, M, Grande-Garcia, A.
Deposit date:2017-04-10
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
6HFN
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BU of 6hfn by Molmil
Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.44965148 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFP
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BU of 6hfp by Molmil
Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.1982286 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFI
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BU of 6hfi by Molmil
Human dihydroorotase mutant F1563A apo structure
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45994723 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFJ
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BU of 6hfj by Molmil
Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFS
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BU of 6hfs by Molmil
Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.34904516 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFF
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BU of 6hff by Molmil
Human dihydroorotase mutant F1563Y apo structure
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.51000106 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFQ
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BU of 6hfq by Molmil
Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.1454246 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFH
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BU of 6hfh by Molmil
Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.44871271 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFR
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BU of 6hfr by Molmil
Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.29949379 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFD
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BU of 6hfd by Molmil
Human dihydroorotase mutant F1563L apo structure
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.869968 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFK
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BU of 6hfk by Molmil
Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.459144 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFE
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BU of 6hfe by Molmil
Human dihydroorotase mutant F1563T apo structure
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.47997439 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFU
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BU of 6hfu by Molmil
Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3997103 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFL
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BU of 6hfl by Molmil
Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
4C6C
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BU of 4c6c by Molmil
Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells.
Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6O
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BU of 4c6o by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 6.0
Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6E
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BU of 4c6e by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 5.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.263 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6N
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BU of 4c6n by Molmil
Crystal structure of the dihydroorotase domain of human CAD E1637T mutant bound to substrate at pH 6.0
Descriptor: CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6I
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BU of 4c6i by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014

 

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