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PDB: 110 件
8A17
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Human PTPRM domains FN3-4, in spacegroup P3221
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ...
著者Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E.
登録日2022-05-31
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8A16
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Human PTPRM domains FN3-4, in spacegroup P212121
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E.
登録日2022-05-31
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8A1F
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Human PTPRK N-terminal domains MAM-Ig-FN1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E.
登録日2022-06-01
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
1MZC
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BU of 1mzc by Molmil
Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound 33a
分子名称: 2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE, FARNESYL DIPHOSPHATE, Protein Farnesyltransferase alpha Subunit, ...
著者deSolms, S.J, Ciccarone, T.M, MacTough, S.C, Shaw, A.W, Buser, C.A, Ellis-Hutchings, M, Fernandes, C, Hamilton, K.A, Huber, H.E, Kohl, N.E, Lobell, R.B, Robinson, R.G, Tsou, N.N, Walsh, E.S, Graham, S.L, Beese, L.S, Taylor, J.S.
登録日2002-10-07
公開日2003-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dual Protein Farnesyltransferase-Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents.
J.Med.Chem., 46, 2003
8B2X
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BU of 8b2x by Molmil
Structure of the type I-G CRISPR effector
分子名称: Type I-G CRISPR Cascade large subunit CSX17
著者Shangguan, Q, Graham, S, Sundaramoorthy, R, White, M.F.
登録日2022-09-15
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structure and mechanism of the type I-G CRISPR effector.
Nucleic Acids Res., 50, 2022
8ANE
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Structure of the type I-G CRISPR effector
分子名称: Cas7, RNA (66-MER)
著者Shangguan, Q, Graham, S, Sundaramoorthy, R, White, M.F.
登録日2022-08-05
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and mechanism of the type I-G CRISPR effector.
Nucleic Acids Res., 50, 2022
7PHY
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BU of 7phy by Molmil
Vaccinia virus E2
分子名称: GLYCEROL, Protein E2
著者Gao, W.N.D, Gao, C, Graham, S.C.
登録日2021-08-19
公開日2021-09-01
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds.
J.Gen.Virol., 103, 2022
6I2M
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Crystal structure of vaccinia virus protein A55 BTB-Back domain in complex with human Cullin-3 N-terminus
分子名称: Cullin-3, Kelch repeat and BTB domain-containing protein A55
著者Gao, G, Graham, S.C.
登録日2018-11-01
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55.
J.Biol.Chem., 294, 2019
3ZYK
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Structure of CALM (PICALM) ANTH domain
分子名称: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYM
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BU of 3zym by Molmil
Structure of CALM (PICALM) in complex with VAMP8
分子名称: GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ...
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYL
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BU of 3zyl by Molmil
Structure of a truncated CALM (PICALM) ANTH domain
分子名称: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
5M61
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BU of 5m61 by Molmil
Clathrin heavy chain N-terminal domain bound to an extended amphiphysin clathrin-box motif
分子名称: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
著者Muenzner, J, Graham, S.C.
登録日2016-10-23
公開日2016-11-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5V
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BU of 5m5v by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 2)
分子名称: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
著者Muenzner, J, Graham, S.C.
登録日2016-10-22
公開日2016-11-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5U
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BU of 5m5u by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 1)
分子名称: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
著者Muenzner, J, Graham, S.C.
登録日2016-10-22
公開日2016-11-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5S
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BU of 5m5s by Molmil
Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin-box motif
分子名称: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
著者Muenzner, J, Graham, S.C.
登録日2016-10-22
公開日2016-11-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5T
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BU of 5m5t by Molmil
Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (Amph4T1)
分子名称: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
著者Muenzner, J, Graham, S.C.
登録日2016-10-22
公開日2016-11-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5R
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BU of 5m5r by Molmil
Clathrin heavy chain N-terminal domain bound to beta2 adaptin clathrin box motif
分子名称: AP-2 complex subunit beta, Clathrin heavy chain 1
著者Muenzner, J, Graham, S.C.
登録日2016-10-22
公開日2016-11-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
3ZED
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BU of 3zed by Molmil
X-ray structure of the birnavirus VP1-VP3 complex
分子名称: CAPSID PROTEIN VP3, GLYCEROL, POTASSIUM ION, ...
著者Bahar, M.W, Sarin, L.P, Graham, S.C, Pang, J, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2012-12-04
公開日2013-01-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a Vp1-Vp3 Complex Suggests How Birnaviruses Package the Vp1 Polymerase.
J.Virol., 87, 2013
3P5J
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BU of 3p5j by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
著者Bubeck, D, Graham, S.C, Jones, E.Y.
登録日2010-10-08
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
2XFX
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BU of 2xfx by Molmil
cattle MHC class I N01301 presenting an 11mer from Theileria parva
分子名称: BETA-2-MICROGLOBULIN, MHC CLASS 1, UNCHARACTERIZED PROTEIN
著者Macdonald, I.K, Harkiolaki, M, Hunt, L, Morrison, W.I, Connelley, T, Graham, S.P, Jones, E.Y, Flower, D.R, Ellis, S.A.
登録日2010-05-28
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mhc Class I Bound to an Immunodominant Theileria Parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors.
Plos Pathog., 6, 2010
3P56
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The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
著者Bubeck, D, Graham, S.C, Jones, E.Y.
登録日2010-10-08
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.06 Å)
主引用文献The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
3ZR5
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BU of 3zr5 by Molmil
STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J.
登録日2011-06-14
公開日2011-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3ZR6
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BU of 3zr6 by Molmil
STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J.
登録日2011-06-14
公開日2011-09-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
2B8V
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Crystal structure of human Beta-secretase complexed with L-L000430,469
分子名称: 3-BENZOYL-N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE, Beta-secretase 1
著者Stachel, S.J, Coburn, C.A, Steele, T.G, Crouthamel, M.-C, Pietrak, B.L, Lai, M.-T, Holloway, M.K, Munshi, S.K, Graham, S.L, Vacca, J.P.
登録日2005-10-10
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformationally biased P3 amide replacements of beta-secretase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
4D5T
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BU of 4d5t by Molmil
Structure of N-terminally truncated A49 from Vaccinia Virus Western Reserve
分子名称: PROTEIN A49R, SULFATE ION
著者Neidel, S, Maluquer de Motes, C, Mansur, D.S, Strnadova, P, Smith, G.L, Graham, S.C.
登録日2014-11-07
公開日2015-01-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Vaccinia Virus Protein A49 is an Unexpected Member of the B-Cell Lymphoma (Bcl)-2 Protein Family
J.Biol.Chem., 290, 2015

224004

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