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PDB: 300 件

1MM6
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crystal structure of the GluR2 ligand binding core (S1S2J) in complex with quisqualate in a non zinc crystal form at 2.15 angstroms resolution
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, GLYCEROL, ...
著者Jin, R, Horning, M, Mayer, M.L, Gouaux, E.
登録日2002-09-03
公開日2003-02-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate
Biochemistry, 41, 2002
1MXU
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments)
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXV
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crystal titration experiments (AMPA co-crystals soaked in 10 mM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY2
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BU of 1my2 by Molmil
crystal titration experiment (AMPA complex control)
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXY
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BU of 1mxy by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY1
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BU of 1my1 by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXX
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crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY3
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BU of 1my3 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY0
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BU of 1my0 by Molmil
crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MQH
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BU of 1mqh by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQI
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Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQG
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Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLYCEROL, SULFATE ION, ...
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQJ
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Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
分子名称: 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MXW
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BU of 1mxw by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY4
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BU of 1my4 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXZ
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BU of 1mxz by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1P1Q
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BU of 1p1q by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, ZINC ION
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-13
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1N
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BU of 1p1n by Molmil
GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-13
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PB7
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BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
分子名称: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB8
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
分子名称: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1P1U
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BU of 1p1u by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form)
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, SULFATE ION
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-14
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PBQ
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BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
分子名称: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-07-29
最終更新日2020-07-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
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CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
分子名称: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1P1O
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BU of 1p1o by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-13
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1W
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BU of 1p1w by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2 precursor, SULFATE ION
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-14
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003

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