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PDB: 300 件
6NJL
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BU of 6njl by Molmil
Architecture and subunit arrangement of native AMPA receptors
分子名称: 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
6NJN
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BU of 6njn by Molmil
Architecture and subunit arrangement of native AMPA receptors
分子名称: 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
2NWW
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BU of 2nww by Molmil
Crystal structure of GltPh in complex with TBOA
分子名称: (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, 425aa long hypothetical proton glutamate symport protein
著者Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K.
登録日2006-11-16
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
2NWX
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BU of 2nwx by Molmil
Crystal structure of GltPh in complex with L-aspartate and sodium ions
分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, PALMITIC ACID, ...
著者Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K.
登録日2006-11-16
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
2NWL
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BU of 2nwl by Molmil
Crystal structure of GltPh in complex with L-Asp
分子名称: ASPARTIC ACID, PALMITIC ACID, glutamate symport protein
著者Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K.
登録日2006-11-15
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
6C13
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BU of 6c13 by Molmil
CryoEM structure of mouse PCDH15-4EC-LHFPL5 complex
分子名称: Protocadherin-15, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gouaux, E, Ge, J, Elferich, J.
登録日2018-01-03
公開日2018-08-15
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (11.33 Å)
主引用文献Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Elife, 7, 2018
6C10
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BU of 6c10 by Molmil
Crystal structure of mouse PCDH15 EC11-EL
分子名称: Protocadherin-15, alpha-D-mannopyranose
著者Gouaux, E, Elferich, J, Ge, J.
登録日2018-01-03
公開日2018-08-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Elife, 7, 2018
6C14
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BU of 6c14 by Molmil
CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex
分子名称: LHFPL tetraspan subfamily member 5 protein, Protocadherin-15
著者Gouaux, E, Elferich, J, Ge, J.
登録日2018-01-03
公開日2018-08-15
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Elife, 7, 2018
1FTM
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BU of 1ftm by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH AMPA AT 1.7 RESOLUTION
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR SUBUNIT 2, ZINC ION
著者Gouaux, E, Armstrong, N.
登録日2000-09-12
公開日2000-11-01
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FTK
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BU of 1ftk by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2I) IN COMPLEX WITH KAINATE AT 1.6 A RESOLUTION
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR SUBUNIT 2
著者Gouaux, E, Armstrong, N.
登録日2000-09-12
公開日2000-11-01
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
4XP1
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BU of 4xp1 by Molmil
X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2015-01-16
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XP5
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BU of 4xp5 by Molmil
X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2015-01-16
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
6NJM
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BU of 6njm by Molmil
Architecture and subunit arrangement of native AMPA receptors
分子名称: 15F1 Fab heavy chain, 15F1 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
4TLL
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BU of 4tll by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 1
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4TLM
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BU of 4tlm by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 2
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4M48
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BU of 4m48 by Molmil
X-ray structure of dopamine transporter elucidates antidepressant mechanism
分子名称: 9D5 antibody, heavy chain, light chain, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2013-08-06
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.955 Å)
主引用文献X-ray structure of dopamine transporter elucidates antidepressant mechanism.
Nature, 503, 2013
6D9G
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BU of 6d9g by Molmil
X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter
分子名称: Antibody heavy chain Fab, Antibody light chain Fab
著者Coleman, J.A, Yang, D, Gouaux, E.
登録日2018-04-29
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
5WKV
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BU of 5wkv by Molmil
Structure of an acid sensing ion channel in a resting state with calcium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Gating mechanisms of acid-sensing ion channels.
Nature, 555, 2018
5WKY
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BU of 5wky by Molmil
Bromide sites in the structure of an acid sensing ion channel in a resting state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
著者Yoder, N, Gouaux, E.
登録日2017-07-25
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography.
PLoS ONE, 13, 2018
3F3A
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BU of 3f3a by Molmil
Crystal Structure of LeuT bound to L-Tryptophan and Sodium
分子名称: SODIUM ION, TETRADECANE, TRYPTOPHAN, ...
著者Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E.
登録日2008-10-30
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
3F3D
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BU of 3f3d by Molmil
Crystal structure of LeuT bound to L-Methionine and sodium
分子名称: METHIONINE, SODIUM ION, Transporter, ...
著者Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E.
登録日2008-10-30
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
6CMC
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BU of 6cmc by Molmil
Barium sites in the structure of a desensitized acid sensing ion channel
分子名称: Acid-sensing ion channel 1, CHLORIDE ION
著者Yoder, N, Gouaux, E.
登録日2018-03-03
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.671 Å)
主引用文献Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography.
PLoS ONE, 13, 2018
8VBY
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BU of 8vby by Molmil
Structure of the human dopamine transporter in complex with beta-CFT, MRS7292 and divalent zinc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, DECANE, ...
著者Srivastava, D.K, Gouaux, E.
登録日2023-12-12
公開日2024-08-07
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structure of the human dopamine transporter and mechanisms of inhibition.
Nature, 632, 2024
1Y20
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BU of 1y20 by Molmil
Crystal structure of the NR1 ligand-binding core in complex with ACPC
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
著者Inanobe, A, Gouaux, E.
登録日2004-11-19
公開日2005-07-12
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
Neuron, 47, 2005
1Y1M
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BU of 1y1m by Molmil
Crystal structure of the NR1 ligand binding core in complex with cycloleucine
分子名称: 1-AMINOCYCLOPENTANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
著者Inanobe, A, Gouaux, E.
登録日2004-11-18
公開日2005-07-12
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
Neuron, 47, 2005

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