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PDB: 5 件
1QMN
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Alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion)
分子名称: ALPHA-1-ANTICHYMOTRYPSIN
著者Gooptu, B, Hazes, B, Lomas, D.A.
登録日1999-10-04
公開日2000-01-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease
Proc.Natl.Acad.Sci.USA, 97, 2000
3DRU
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Crystal Structure of Gly117Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DRM
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2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
4PYW
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1.92 angstrom crystal structure of A1AT:TTAI ternary complex
分子名称: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
著者Nyon, M.P, Day, J, Gooptu, B.
登録日2014-03-28
公開日2015-06-10
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015
3NE4
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1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin
分子名称: Alpha-1-antitrypsin
著者Patschull, A.O.M, Gooptu, B, Segu, L.
登録日2010-06-08
公開日2011-12-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution
Acta Crystallogr.,Sect.F, 67, 2011

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件を2024-07-24に公開中

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