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PDB: 72 results
3U7E
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BU of 3u7e by Molmil
Crystal structure of mPNKP catalytic fragment (D170A)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7G
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BU of 3u7g by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3JVE
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BU of 3jve by Molmil
Crystal Structure of the Sixth BRCT Domain of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
3QZC
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BU of 3qzc by Molmil
Structure of the periplasmic stress response protein CpxP
Descriptor: Periplasmic protein CpxP, ZINC ION
Authors:Thede, G.L, Edwards, R.A, Glover, J.N.M.
Deposit date:2011-03-04
Release date:2011-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the Periplasmic Stress Response Protein CpxP.
J.Bacteriol., 193, 2011
3UEO
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BU of 3ueo by Molmil
Crystal structure of TopBP1 BRCT4/5 domains in complex with a phospho-peptide
Descriptor: DNA topoisomerase 2-binding protein 1, phospho-peptide
Authors:Leung, C.C, Glover, J.N.M.
Deposit date:2011-10-31
Release date:2013-07-03
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Structure, 21, 2013
3UEN
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BU of 3uen by Molmil
Crystal structure of TopBP1 BRCT4/5 domains
Descriptor: DNA topoisomerase 2-binding protein 1, GLYCEROL, THIOCYANATE ION
Authors:Leung, C.C, Glover, J.N.M.
Deposit date:2011-10-31
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Structure, 21, 2013
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ONN
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BU of 4onn by Molmil
Crystal structure of human Mms2/Ubc13 - BAY 11-7082
Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
Descriptor: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-02-11
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4NR3
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BU of 4nr3 by Molmil
Crystal Structure of a human Mms2/Ubc13 L121G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4NRI
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BU of 4nri by Molmil
Crystal Structure of a human Mms2/Ubc13 A122G mutant
Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
1N5O
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BU of 1n5o by Molmil
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Glover, J.N.M.
Deposit date:2002-11-06
Release date:2002-12-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
J.Biol.Chem., 278, 2003
2F9D
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BU of 2f9d by Molmil
2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
Deposit date:2005-12-05
Release date:2006-01-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
1A02
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BU of 1a02 by Molmil
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Descriptor: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ...
Authors:Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C.
Deposit date:1997-12-08
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
1DVO
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BU of 1dvo by Molmil
THE X-RAY CRYSTAL STRUCTURE OF FINO, A REPRESSOR OF BACTERIAL CONJUGATION
Descriptor: FERTILITY INHIBITION PROTEIN O
Authors:Ghetu, A.F, Gubbins, M.J, Frost, L.S, Glover, J.N.M.
Deposit date:2000-01-21
Release date:2000-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the bacterial conjugation repressor finO.
Nat.Struct.Biol., 7, 2000
1JNX
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BU of 1jnx by Molmil
Crystal structure of the BRCT repeat region from the breast cancer associated protein, BRCA1
Descriptor: BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, NICKEL (II) ION
Authors:Williams, R.S, Green, R, Glover, J.N.M.
Deposit date:2001-07-26
Release date:2001-09-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1.
Nat.Struct.Biol., 8, 2001
1J74
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BU of 1j74 by Molmil
Crystal Structure of Mms2
Descriptor: MMS2
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-15
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1MN4
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BU of 1mn4 by Molmil
Structure of Ndt80 (Residues 59-340) DNA-binding domain core
Descriptor: NDT80 PROTEIN
Authors:Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M.
Deposit date:2002-09-04
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
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