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6NNH
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Structure of Closed state of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and cycloguanil
Descriptor: 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, COBALT (II) ION, Dihydrofolate reductase, ...
Authors:Giudice, J.H.P, Ribeiro, J.A, Dias, M.V.B.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.523 Å)
Cite:Crystal structures of the closed form of Mycobacterium tuberculosis dihydrofolate reductase in complex with dihydrofolate and antifolates.
Acta Crystallogr D Struct Biol, 75, 2019

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