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PDB: 41 件
8SLV
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Structure of a salivary alpha-glucosidase from the mosquito vector Aedes aegypti.
分子名称: 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gittis, A.G, Williams, A.E, Garboczi, D, Calvo, E.
登録日2023-04-24
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and functional comparisons of salivary alpha-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus.
Insect Biochem.Mol.Biol., 167, 2024
1NZN
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Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
分子名称: Fission protein Fis1p, GLYCEROL, SULFATE ION
著者Gittis, A.G, Dohm, J.A, Hill, R.B.
登録日2003-02-18
公開日2004-03-02
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
Proteins, 54, 2004
2ENB
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CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
分子名称: STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Libson, A, Gittis, A, Lattman, E.E.
登録日1994-03-23
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
Biochemistry, 33, 1994
1GEN
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C-TERMINAL DOMAIN OF GELATINASE A
分子名称: CALCIUM ION, CHLORIDE ION, GELATINASE A, ...
著者Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E.
登録日1995-07-19
公開日1996-08-17
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
Nat.Struct.Biol., 2, 1995
1AHQ
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RECOMBINANT ACTOPHORIN
分子名称: ACTOPHORIN
著者Leonard, S.A, Gittis, A.G, Petrella, E.C, Pollard, T.D, Lattman, E.E.
登録日1997-04-10
公開日1997-09-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the actin-binding protein actophorin from Acanthamoeba.
Nat.Struct.Biol., 4, 1997
6OHG
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Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4F12 Heavy chain, ...
著者Garboczi, D.N, Singh, K, Gittis, A.G.
登録日2019-04-05
公開日2020-06-17
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.385 Å)
主引用文献Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.
Commun Biol, 3, 2020
6V4C
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Culex quinquefasciatus D7 long form 1- CxD7L1 in complex with ADP
分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Calvo, E, Garboczi, D.N, Martin-Martin, I, Gittis, A.G.
登録日2019-11-27
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals.
Nat Commun, 11, 2020
6CJ6
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Structure of the poxvirus protein F9
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ...
著者Diesterbeck, U.S, Gittis, A.G, Garboczi, D.N, Moss, B.
登録日2018-02-26
公開日2019-03-06
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The 2.1 angstrom structure of protein F9 and its comparison to L1, two components of the conserved poxvirus entry-fusion complex.
Sci Rep, 8, 2018
7TXW
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Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOL, ...
著者Singh, K, Gittis, A.G, Garboczi, D.N.
登録日2022-02-10
公開日2023-04-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Npj Vaccines, 8, 2023
1HC8
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CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
分子名称: 58 NUCLEOTIDE RIBOSOMAL 23S RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ...
著者Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G.
登録日2001-04-27
公開日2002-05-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Compact RNA Tertiary Structure Contains a Buried Backbone-K+ Complex
J.Mol.Biol., 318, 2002
4QVB
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Mycobacterium tuberculosis protein Rv1155 in complex with co-enzyme F420
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, COENZYME F420, ...
著者Mashalidis, E.H, Gittis, A.G, Tomczak, A, Abell, C, Barry III, C.E, Garboczi, D.N.
登録日2014-07-14
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis.
Protein Sci., 24, 2015
2I9L
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Structure of Fab 7D11 from a neutralizing antibody against the poxvirus L1 protein
分子名称: Antibody 7D11 heavy chain, Antibody 7D11 light chain, GLYCEROL, ...
著者Su, H.P, Golden, J.W, Gittis, A.G, Moss, B, Hooper, J.W, Garboczi, D.N.
登録日2006-09-05
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein
Virology, 368, 2007
3BIK
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Crystal Structure of the PD-1/PD-L1 Complex
分子名称: GLYCEROL, Programmed cell death 1 ligand 1, Programmed cell death protein 1
著者Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N.
登録日2007-11-30
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1ZJE
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12mer-spd
分子名称: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
著者Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
登録日2005-04-28
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
7KCG
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Salivary protein from Culex quiquefasciatus that belongs to the Cysteine and Tryptophan-Rich (CWRC) family
分子名称: 16 kDa salivary peptide, FORMIC ACID
著者Garboczi, N.D, Gittis, A.G, Kern, O, Martin-Martin, I, Calvo, E.
登録日2020-10-05
公開日2021-06-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties
Curr Res Struct Biol, 3, 2021
7KC8
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Salivary protein from Culex quinquefasciatus that belongs to the Cysteins and Tryptophan-Rich (CWRC) family
分子名称: 16.4 kDa salivary peptide, ACETIC ACID
著者Garboczi, D.N, Gittis, A.G, Kern, O, Martin-Martin, I.
登録日2020-10-05
公開日2021-06-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties
Curr Res Struct Biol, 3, 2021
5EJ0
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The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ...
著者Singh, K, Gittis, A.G, Gitti, R.K, Ostazesky, S.A, Su, H.P, Garboczi, D.N.
登録日2015-10-30
公開日2016-03-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-Glucose.
J.Virol., 90, 2016
7U1N
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Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein
分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-ETHOXYETHANOL, ...
著者Alvarenga, P.H, Gittis, A.G, Garboczi, D.N, Andersen, J.F.
登録日2022-02-21
公開日2022-05-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Insect Biochem.Mol.Biol., 146, 2022
1ZJG
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13mer-co
分子名称: 5'-D(*AP*TP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*CP*A)-3', COBALT HEXAMMINE(III), ...
著者Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
登録日2005-04-28
公開日2005-05-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1ZJF
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12mer-spd-P4N
分子名称: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
著者Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
登録日2005-04-28
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1MUT
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BU of 1mut by Molmil
NMR STUDY OF MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE
分子名称: NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE
著者Abeygunawardana, C, Weber, D.J, Gittis, A.G, Frick, D.N, Lin, J, Miller, A.-F, Bessman, M.J, Mildvan, A.S.
登録日1995-09-14
公開日1996-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase.
Biochemistry, 34, 1995
2OEO
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BU of 2oeo by Molmil
Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D
分子名称: CALCIUM ION, Staphylococcal thermonuclease, THYMIDINE-3',5'-DIPHOSPHATE
著者Reynald, R.L, Lattman, E.E, Gittis, A.G.
登録日2006-12-30
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Buried Charges and Water in the Protein Interior: Reality or Fiction?
To be Published
2SOB
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BU of 2sob by Molmil
SN-OB, OB-FOLD SUB-DOMAIN OF STAPHYLOCOCCAL NUCLEASE, NMR, 10 STRUCTURES
分子名称: STAPHYLOCOCCAL NUCLEASE
著者Alexandrescu, A.T, Gittis, A.G, Abeygunawardana, C, Shortle, D.
登録日1995-09-15
公開日1995-12-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of a stable "OB-fold" sub-domain isolated from staphylococcal nuclease.
J.Mol.Biol., 250, 1995
2SNM
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IN A STAPHYLOCOCCAL NUCLEASE MUTANT THE SIDE-CHAIN of A LYSINE REPLACING VALINE 66 IS FULLY BURIED IN THE HYDROPHOBIC CORE
分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Stites, W.E, Gittis, A.G, Lattman, E.E, Shortle, D.
登録日1991-04-03
公開日1993-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献In a staphylococcal nuclease mutant the side-chain of a lysine replacing valine 66 is fully buried in the hydrophobic core.
J.Mol.Biol., 221, 1991
1ENC
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CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Libson, A, Gittis, A, Lattman, E.E.
登録日1994-02-14
公開日1994-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
Biochemistry, 33, 1994

 

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