2HHD
| OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA-CHAINS IN HUMAN AND BOVINE HEMOGLOBIN | Descriptor: | HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Gilliland, G.L, Pechik, I, Fronticelli, C, Ji, X. | Deposit date: | 1994-09-29 | Release date: | 1995-01-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic, molecular modeling, and biophysical characterization of the valine beta 67 (E11)-->threonine variant of hemoglobin. Biochemistry, 35, 1996
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2HHE
| OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN | Descriptor: | HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gilliland, G.L, Pechik, I, Fronticelli, C, Ji, X. | Deposit date: | 1994-09-29 | Release date: | 1995-01-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Chloride ion independence of the Bohr effect in a mutant human hemoglobin beta (V1M+H2deleted). J.Biol.Chem., 269, 1994
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1A2Q
| SUBTILISIN BPN' MUTANT 7186 | Descriptor: | ACETONE, CALCIUM ION, SUBTILISIN BPN' | Authors: | Gilliland, G.L, Whitlow, M, Howard, A.J. | Deposit date: | 1998-01-08 | Release date: | 1998-04-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding. Biochemistry, 28, 1989
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1DBF
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1CMS
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6GSY
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | GLUTATHIONE, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3 | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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6GSV
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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3G6A
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4EUG
| Crystallographic and Enzymatic Studies of an Active Site Variant H187Q of Escherichia Coli Uracil DNA Glycosylase: Crystal Structures of Mutant H187Q and its Uracil Complex | Descriptor: | PROTEIN (GLYCOSYLASE) | Authors: | Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. | Deposit date: | 1998-12-27 | Release date: | 1999-07-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187. Biochemistry, 38, 1999
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2F6L
| X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis | Descriptor: | Chorismate mutase | Authors: | Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E. | Deposit date: | 2005-11-29 | Release date: | 2005-12-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. J.Bacteriol., 188, 2006
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3TES
| Crystal Structure of Tencon | Descriptor: | Tencon | Authors: | Luo, J, Jacobs, S, Teplyakov, A, Obmolova, G, O'Neil, K, Gilliland, G. | Deposit date: | 2011-08-15 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Design of novel FN3 domains with high stability by a consensus sequence approach. Protein Eng.Des.Sel., 25, 2012
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3TEU
| Crystal structure of fibcon | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Fibcon | Authors: | Luo, J, Jacobs, S, Teplyakov, A, Obmolova, G, O'Neil, K, Gilliland, G. | Deposit date: | 2011-08-15 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.002 Å) | Cite: | Design of novel FN3 domains with high stability by a consensus sequence approach. Protein Eng.Des.Sel., 25, 2012
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7RSA
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6GSW
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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6GSU
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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6GSX
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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6GST
| FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | Descriptor: | GLUTATHIONE, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3 | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1996-01-26 | Release date: | 1996-11-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry, 35, 1996
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3FYG
| CRYSTAL STRUCTURE OF TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE | Descriptor: | (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, MU CLASS TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE OF ISOENZYME | Authors: | Xiao, G, Parsons, J.F, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1997-08-07 | Release date: | 1999-06-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine. J.Mol.Biol., 281, 1998
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4GST
| REACTION COORDINATE MOTION IN AN SNAR REACTION CATALYZED BY GLUTATHIONE TRANSFERASE | Descriptor: | 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION | Authors: | Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1993-07-20 | Release date: | 1993-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase. Biochemistry, 32, 1993
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5FWG
| TETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE | Descriptor: | (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, TETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE MU CLASS | Authors: | Parsons, J.F, Xiao, G, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1997-11-08 | Release date: | 1999-01-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enzymes harboring unnatural amino acids: mechanistic and structural analysis of the enhanced catalytic activity of a glutathione transferase containing 5-fluorotryptophan. Biochemistry, 37, 1998
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4HAG
| Crystal structure of fc-fragment of human IgG2 antibody (centered crystal form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | Authors: | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | Deposit date: | 2012-09-26 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface. Mol.Immunol., 56, 2013
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4HAF
| Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | Authors: | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | Deposit date: | 2012-09-26 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface. Mol.Immunol., 56, 2013
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2A45
| Crystal structure of the complex between thrombin and the central "E" region of fibrin | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Fibrinogen alpha chain, Fibrinogen beta chain, ... | Authors: | Pechik, I, Madrazo, J, Gilliland, G.L, Medved, L. | Deposit date: | 2005-06-27 | Release date: | 2006-05-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry, 45, 2006
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4YDY
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5KNG
| CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9 | Descriptor: | DARPIN 6G9, GLYCEROL, PHOSPHATE ION | Authors: | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | Deposit date: | 2016-06-28 | Release date: | 2016-12-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Conformational flexibility of an anti-IL-13 DARPin. Protein Eng. Des. Sel., 30, 2017
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