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PDB: 6 results

8EHH
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BU of 8ehh by Molmil
Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution
Descriptor: (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
Authors:Power, P, Ghiglione, B, Bonomo, R.A, Rodriguez, M.M, Gutkind, G, Klinke, S.
Deposit date:2022-09-14
Release date:2023-09-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Biochemical and structural evidences of the activity of relebactam as inhibitor of the extended-spectrum beta-lactamase CTX-M-96.
To be published
3ZNY
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BU of 3zny by Molmil
Crystal structure of the class A extended-spectrum beta-lactamase CTX- M-96, a natural D240G mutant derived from CTX-M-12
Descriptor: CTX-M-12A ENZYME
Authors:Power, P, Herman, R, Bouillenne, F, Ghiglione, B, Rodriguez, M.M, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E.
Deposit date:2013-02-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural and Kinetic Insights Into the "Ceftazidimase" Behavior of the Extended-Spectrum Beta-Lactamase Ctx-M-96.
Biochemistry, 54, 2015
8EK9
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BU of 8ek9 by Molmil
Crystal structure of the class A carbapenemase CRH-1 in complex with avibactam at 1.4 Angstrom resolution
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
Authors:Power, P, Brunetti, F, Ghiglione, B, Guardabassi, L, Gutkind, G, Klinke, S.
Deposit date:2022-09-20
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC beta-Lactamases.
Antimicrob.Agents Chemother., 67, 2023
8EHU
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BU of 8ehu by Molmil
Crystal structure of the environmental CRH-1 class A carbapenemase at 1.1 Angstrom resolution
Descriptor: Beta-lactamase
Authors:Power, P, Brunetti, F, Ghiglione, B, Guardabassi, L, Gutkind, G, Klinke, S.
Deposit date:2022-09-14
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC beta-Lactamases.
Antimicrob.Agents Chemother., 67, 2023
6BN3
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BU of 6bn3 by Molmil
CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase
Authors:Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S.
Deposit date:2017-11-16
Release date:2018-11-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam.
Antimicrob.Agents Chemother., 65, 2021
6BPF
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BU of 6bpf by Molmil
CTX-M-151 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 Angstrom resolution
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
Authors:Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S.
Deposit date:2017-11-23
Release date:2018-11-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.318 Å)
Cite:Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam.
Antimicrob.Agents Chemother., 65, 2021

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