1VPT
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![BU of 1vpt by Molmil](/molmil-images/mine/1vpt) | AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE | Descriptor: | S-ADENOSYLMETHIONINE, VP39 | Authors: | Hodel, A.E, Gershon, P.D, Shi, X, Quiocho, F.A. | Deposit date: | 1996-03-20 | Release date: | 1996-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends. Cell(Cambridge,Mass.), 85, 1996
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2VP3
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![BU of 2vp3 by Molmil](/molmil-images/mine/2vp3) | |
1P39
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![BU of 1p39 by Molmil](/molmil-images/mine/1p39) | |
4DCG
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![BU of 4dcg by Molmil](/molmil-images/mine/4dcg) | VACCINIA METHYLTRANSFERASE VP39 MUTANT D182A COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 7-METHYLGUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1998-07-13 | Release date: | 1999-07-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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1VP9
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![BU of 1vp9 by Molmil](/molmil-images/mine/1vp9) | |
1VP3
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![BU of 1vp3 by Molmil](/molmil-images/mine/1vp3) | |
2GAF
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![BU of 2gaf by Molmil](/molmil-images/mine/2gaf) | Crystal Structure of the Vaccinia Polyadenylate Polymerase Heterodimer (apo form) | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2006-03-08 | Release date: | 2006-05-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol.Cell, 22, 2006
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2GA9
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![BU of 2ga9 by Molmil](/molmil-images/mine/2ga9) | Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound ATP-gamma-S | Descriptor: | CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2006-03-08 | Release date: | 2006-05-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol.Cell, 22, 2006
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1V39
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1EAM
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![BU of 1eam by Molmil](/molmil-images/mine/1eam) | VACCINIA METHYLTRANSFERASE VP39 MUTANT (EC: 2.7.7.19) | Descriptor: | PROTEIN (VP39), S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1999-01-26 | Release date: | 1999-06-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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1EQA
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![BU of 1eqa by Molmil](/molmil-images/mine/1eqa) | VACCINIA METHYLTRANSFERASE VP39 MUTANT E233Q COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 7-METHYLGUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1999-01-05 | Release date: | 1999-07-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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1BKY
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![BU of 1bky by Molmil](/molmil-images/mine/1bky) | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M1CYT AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 1-METHYLCYTOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1998-07-13 | Release date: | 1999-07-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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1B42
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![BU of 1b42 by Molmil](/molmil-images/mine/1b42) | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M1ADE AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 6-AMINO-1-METHYLPURINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1999-01-05 | Release date: | 1999-07-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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1AV6
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![BU of 1av6 by Molmil](/molmil-images/mine/1av6) | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M7G CAPPED RNA HEXAMER AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, RNA (5'-R(*GP*AP*AP*AP*AP*A)-3'), ... | Authors: | Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1997-09-26 | Release date: | 1998-02-25 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme. Mol.Cell, 1, 1998
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1JSZ
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![BU of 1jsz by Molmil](/molmil-images/mine/1jsz) | Crystal Structure Analysis of N7,9-dimethylguanine-VP39 complex | Descriptor: | 7,9-DIMETHYLGUANINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Oguro, A, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2001-08-19 | Release date: | 2002-07-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap. Biochemistry, 41, 2002
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1JTE
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![BU of 1jte by Molmil](/molmil-images/mine/1jte) | Crystal Structure Analysis of VP39 F180W mutant | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Oguro, A, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2001-08-20 | Release date: | 2002-07-10 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap. Biochemistry, 41, 2002
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1JTF
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![BU of 1jtf by Molmil](/molmil-images/mine/1jtf) | Crystal Structure Analysis of VP39-F180W mutant and m7GpppG complex | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Oguro, A, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2001-08-20 | Release date: | 2002-07-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap. Biochemistry, 41, 2002
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3OWG
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![BU of 3owg by Molmil](/molmil-images/mine/3owg) | Crystal structure of vaccinia virus Polyadenylate polymerase(vp55) | Descriptor: | Poly(A) polymerase catalytic subunit | Authors: | Li, C, Li, H, Zhou, S, Gershon, P.D, Poulos, T.L. | Deposit date: | 2010-09-17 | Release date: | 2011-09-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid. Acta Crystallogr.,Sect.D, 69, 2013
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3ERC
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![BU of 3erc by Molmil](/molmil-images/mine/3erc) | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase with three fragments of RNA and 3'-deoxy ATP | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, ... | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | Deposit date: | 2008-10-01 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
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3ER9
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![BU of 3er9 by Molmil](/molmil-images/mine/3er9) | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ... | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | Deposit date: | 2008-10-01 | Release date: | 2009-06-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
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3ER8
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![BU of 3er8 by Molmil](/molmil-images/mine/3er8) | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with two fragments of RNA | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ... | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | Deposit date: | 2008-10-01 | Release date: | 2009-06-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
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3MAG
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![BU of 3mag by Molmil](/molmil-images/mine/3mag) | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3ADE AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 6-AMINO-3-METHYLPURINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. | Deposit date: | 1998-07-12 | Release date: | 1999-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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3MCT
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![BU of 3mct by Molmil](/molmil-images/mine/3mct) | VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE | Descriptor: | 3-METHYLCYTOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39 | Authors: | Hu, G, Gershon, P.D, Hodel, A.E, Quiocho, F.A. | Deposit date: | 1999-01-05 | Release date: | 1999-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
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