5GHI
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![BU of 5ghi by Molmil](/molmil-images/mine/5ghi) | Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.211 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHO
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![BU of 5gho by Molmil](/molmil-images/mine/5gho) | Crystal structure of human MTH1(G2K/D120A mutant) in complex with 8-oxo-dGTP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.191 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHN
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![BU of 5ghn by Molmil](/molmil-images/mine/5ghn) | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.391 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHM
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![BU of 5ghm by Molmil](/molmil-images/mine/5ghm) | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHQ
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![BU of 5ghq by Molmil](/molmil-images/mine/5ghq) | Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.181 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHJ
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![BU of 5ghj by Molmil](/molmil-images/mine/5ghj) | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHP
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![BU of 5ghp by Molmil](/molmil-images/mine/5ghp) | Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2016-06-20 | Release date: | 2017-01-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.192 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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1V8Z
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![BU of 1v8z by Molmil](/molmil-images/mine/1v8z) | X-ray crystal structure of the Tryptophan Synthase b2 Subunit from Hyperthermophile, Pyrococcus furiosus | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, Tryptophan synthase beta chain 1 | Authors: | Hioki, Y, Ogasahara, K, Lee, S.J, Ma, J, Ishida, M, Yamagata, Y, Matsuura, Y, Ota, M, Kuramitsu, S, Yutani, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-01-15 | Release date: | 2005-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The crystal structure of the tryptophan synthase beta subunit from the hyperthermophile Pyrococcus furiosus. Investigation of stabilization factors Eur.J.Biochem., 271, 2004
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1VGN
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![BU of 1vgn by Molmil](/molmil-images/mine/1vgn) | Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1) | Descriptor: | 3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE, ACETIC ACID, Beta-lactamase IMP-1, ... | Authors: | Kurosaki, H, Yamaguchi, Y, Higashi, T, Soga, K, Matsueda, S, Misumi, S, Yamagata, Y, Arakawa, Y, Goto, M. | Deposit date: | 2004-04-27 | Release date: | 2005-06-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Irreversible Inhibition of Metallo-beta-lactamase (IMP-1) by 3-(3-Mercaptopropionylsulfanyl)propionic Acid Pentafluorophenyl Ester Angew.Chem.Int.Ed.Engl., 44, 2005
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1WUP
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![BU of 1wup by Molmil](/molmil-images/mine/1wup) | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81E) | Descriptor: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | Authors: | Yamaguchi, Y, Yamagata, Y, Goto, M. | Deposit date: | 2004-12-08 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography. J.Biol.Chem., 280, 2005
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1WUO
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![BU of 1wuo by Molmil](/molmil-images/mine/1wuo) | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81A) | Descriptor: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | Authors: | Yamaguchi, Y, Yamagata, Y, Goto, M. | Deposit date: | 2004-12-08 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography. J.Biol.Chem., 280, 2005
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1GB6
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![BU of 1gb6 by Molmil](/molmil-images/mine/1gb6) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1GFH
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![BU of 1gfh by Molmil](/molmil-images/mine/1gfh) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-12-04 | Release date: | 2000-12-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
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1GFT
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![BU of 1gft by Molmil](/molmil-images/mine/1gft) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-12-04 | Release date: | 2000-12-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
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1GBY
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![BU of 1gby by Molmil](/molmil-images/mine/1gby) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1GDX
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![BU of 1gdx by Molmil](/molmil-images/mine/1gdx) | |
1GEZ
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![BU of 1gez by Molmil](/molmil-images/mine/1gez) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF4
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![BU of 1gf4 by Molmil](/molmil-images/mine/1gf4) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1G42
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![BU of 1g42 by Molmil](/molmil-images/mine/1g42) | STRUCTURE OF 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE (LINB) FROM SPHINGOMONAS PAUCIMOBILIS COMPLEXED WITH 1,2-DICHLOROPROPANE | Descriptor: | 1,2-DICHLORO-PROPANE, 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, ACETATE ION, ... | Authors: | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | Deposit date: | 2000-10-26 | Release date: | 2001-10-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition. Biochemistry, 41, 2002
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1GE1
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![BU of 1ge1 by Molmil](/molmil-images/mine/1ge1) | |
1GEV
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![BU of 1gev by Molmil](/molmil-images/mine/1gev) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF5
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![BU of 1gf5 by Molmil](/molmil-images/mine/1gf5) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GB7
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![BU of 1gb7 by Molmil](/molmil-images/mine/1gb7) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1GBX
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![BU of 1gbx by Molmil](/molmil-images/mine/1gbx) | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-06-26 | Release date: | 2000-07-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
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1GF7
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![BU of 1gf7 by Molmil](/molmil-images/mine/1gf7) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability Biochemistry, 40, 2001
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