8E8B
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8E8J
| Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*CP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2022-08-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
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8E8G
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8E85
| Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mn2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*CP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2022-08-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
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8E8F
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8E8D
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8E8C
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8E89
| Human DNA polymerase eta-DNA-rU-ended primer-binary complex | Descriptor: | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*U)-3') | Authors: | Chang, C, Gao, Y. | Deposit date: | 2022-08-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
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8E8H
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8E8E
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8E88
| Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2022-08-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
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8E8K
| Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2022-08-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
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3P6Y
| CF Im25-CF Im68-UGUAA complex | Descriptor: | 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | Authors: | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | Deposit date: | 2010-10-11 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex To be Published
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3P5T
| CFIm25-CFIm68 complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | Authors: | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | Deposit date: | 2010-10-11 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex To be Published
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8EFK
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA | Descriptor: | 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(P*TP*TP*TP*TP*GP*GP*CP*TP*TP*TP*TP*GP*CP*CP*(2DA))-3'), Lates calcarifer DNA polymerase theta, ... | Authors: | Li, C, Zhu, H, Sun, J, Gao, Y. | Deposit date: | 2022-09-08 | Release date: | 2022-12-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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8EF9
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ... | Authors: | Li, C, Zhu, H, Sun, J, Gao, Y. | Deposit date: | 2022-09-08 | Release date: | 2022-12-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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8EFC
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*CP*TP*GP*TP*GP*AP*GP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*CP*CP*TP*CP*AP*CP*AP*G)-3'), ... | Authors: | Li, C, Zhu, H, Sun, J, Gao, Y. | Deposit date: | 2022-09-08 | Release date: | 2022-12-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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3MXX
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3N0D
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3EHQ
| Crystal Structure of Human Osteoclast Stimulating Factor | Descriptor: | 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 | Authors: | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | Deposit date: | 2008-09-14 | Release date: | 2009-08-04 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
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3N0E
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4DM4
| The conserved domain of yeast Cdc73 | Descriptor: | Cell division control protein 73 | Authors: | Chen, H, Shi, N, Gao, Y, Li, X, Niu, L, Teng, M. | Deposit date: | 2012-02-06 | Release date: | 2012-08-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold. Acta Crystallogr.,Sect.D, 68, 2012
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6L1W
| Zinc-finger Antiviral Protein (ZAP) bound to RNA | Descriptor: | RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION, Zinc finger CCCH-type antiviral protein 1 | Authors: | Luo, X, Wang, X, Gao, Y, Zhu, J, Liu, S, Gao, G, Gao, P. | Deposit date: | 2019-09-30 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein. Cell Rep, 30, 2020
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2DAP
| C. GLUTAMICUM DAP DEHYDROGENASE IN COMPLEX WITH DAP | Descriptor: | 2,6-DIAMINOPIMELIC ACID, DIAMINOPIMELIC ACID DEHYDROGENASE | Authors: | Scapin, G, Cirilli, M, Reddy, S.G, Gao, Y, Vederas, J.C, Blanchard, J.S. | Deposit date: | 1997-12-23 | Release date: | 1998-04-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Substrate and inhibitor binding sites in Corynebacterium glutamicum diaminopimelate dehydrogenase. Biochemistry, 37, 1998
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7M7S
| Human DNA Pol eta S113A with dT-ended primer and 0.1 mM dAMPNPP | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | Authors: | Gregory, M.T, Gao, Y, Yang, W. | Deposit date: | 2021-03-28 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction. Proc.Natl.Acad.Sci.USA, 118, 2021
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