8EFK
 
 | | Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA | | 分子名称: | 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(P*TP*TP*TP*TP*GP*GP*CP*TP*TP*TP*TP*GP*CP*CP*(2DA))-3'), Lates calcarifer DNA polymerase theta, ... | | 著者 | Li, C, Zhu, H, Sun, J, Gao, Y. | | 登録日 | 2022-09-08 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of DNA polymerase theta mediated DNA end joining.
Nucleic Acids Res., 51, 2023
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8EF9
 | | Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ... | | 著者 | Li, C, Zhu, H, Sun, J, Gao, Y. | | 登録日 | 2022-09-08 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of DNA polymerase theta mediated DNA end joining.
Nucleic Acids Res., 51, 2023
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8E85
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8E89
 | | Human DNA polymerase eta-DNA-rU-ended primer-binary complex | | 分子名称: | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*U)-3') | | 著者 | Chang, C, Gao, Y. | | 登録日 | 2022-08-25 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity.
J.Biol.Chem., 299, 2023
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8E8E
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8E8K
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8E8B
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8E8G
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8E88
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8E8D
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8E8J
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8E86
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8E8A
 | | Human DNA polymerase eta-DNA-dT-ended primer binary complex | | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta | | 著者 | Chang, C, Gao, Y. | | 登録日 | 2022-08-25 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity.
J.Biol.Chem., 299, 2023
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8E8F
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8E87
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8E8C
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8E8H
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4FMM
 | | Dimeric Sec14 family homolog 3 from Saccharomyces cerevisiae presents some novel features of structure that lead to a surprising "dimer-monomer" state change induced by substrate binding | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphatidylinositol transfer protein PDR16 | | 著者 | Yuan, Y, Zhao, W, Wang, X, Gao, Y, Niu, L, Teng, M. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Dimeric Sfh3 has structural changes in its binding pocket that are associated with a dimer-monomer state transformation induced by substrate binding.
Acta Crystallogr.,Sect.D, 69, 2013
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3EHR
 | | Crystal Structure of Human Osteoclast Stimulating Factor | | 分子名称: | Osteoclast-stimulating factor 1 | | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | | 登録日 | 2008-09-14 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
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7M7R
 | | Human DNA Pol eta S113A with rA-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M87
 | | Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 230 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7Q
 | | Human DNA Pol eta S113A with dT-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M81
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 100 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M85
 | | Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 80 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M82
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 300 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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