1WDG
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![BU of 1wdg by Molmil](/molmil-images/mine/1wdg) | crystal structure of MHV spike protein fusion core | 分子名称: | E2 glycoprotein | 著者 | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | 登録日 | 2004-05-14 | 公開日 | 2004-06-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE J.Biol.Chem., 279, 2004
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6KL9
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![BU of 6kl9 by Molmil](/molmil-images/mine/6kl9) | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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5X4R
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![BU of 5x4r by Molmil](/molmil-images/mine/5x4r) | Structure of the N-terminal domain (NTD) of MERS-CoV spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | 著者 | Yuan, Y, Zhang, Y, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-02-14 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X5B
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![BU of 5x5b by Molmil](/molmil-images/mine/5x5b) | Prefusion structure of SARS-CoV spike glycoprotein, conformation 2 | 分子名称: | Spike glycoprotein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5F1N
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![BU of 5f1n by Molmil](/molmil-images/mine/5f1n) | MHC complexed to 11mer peptide | 分子名称: | Beta-2-microglobulin, MHC class I antigen, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1 | 著者 | Liu, J, Chai, Y, Qi, J, Gao, G.F. | 登録日 | 2015-11-30 | 公開日 | 2016-11-30 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I J Immunol., 197, 2016
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5XJ3
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![BU of 5xj3 by Molmil](/molmil-images/mine/5xj3) | Complex structure of ipilimumab-scFv and CTLA-4 | 分子名称: | Cytotoxic T-lymphocyte protein 4, ipilimumab-VH, ipilimumab-VL | 著者 | He, M, Chai, Y, Qi, J, Tong, Z, Tan, S, Gao, G.F. | 登録日 | 2017-04-29 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies Oncotarget, 8, 2017
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4MX5
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![BU of 4mx5 by Molmil](/molmil-images/mine/4mx5) | Structure of ricin A chain bound with benzyl-(2-(2-amino-4-oxo-3,4-dihydropteridine-7-carboxamido)ethyl)carbamate | 分子名称: | Ricin A chain, benzyl (2-{[(2-amino-4-oxo-3,4-dihydropteridin-7-yl)carbonyl]amino}ethyl)carbamate | 著者 | Jasheway, K.R, Robertus, J.D, Wiget, P.A, Manzano, L.A, Pruet, J.M, Gao, G, Saito, R, Monzingo, A.F, Anslyn, E.V. | 登録日 | 2013-09-25 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics. Bioorg.Med.Chem.Lett., 23, 2013
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5X5C
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![BU of 5x5c by Molmil](/molmil-images/mine/5x5c) | Prefusion structure of MERS-CoV spike glycoprotein, conformation 1 | 分子名称: | S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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6KLB
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![BU of 6klb by Molmil](/molmil-images/mine/6klb) | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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4LNR
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![BU of 4lnr by Molmil](/molmil-images/mine/4lnr) | The structure of HLA-B*35:01 in complex with the peptide (RPQVPLRPMTY) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Cheng, H, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2013-07-12 | 公開日 | 2014-07-23 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex. J.Biol.Chem., 289, 2014
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5X4S
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![BU of 5x4s by Molmil](/molmil-images/mine/5x4s) | Structure of the N-terminal domain (NTD)of SARS-CoV spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yuan, Y, Zhang, Y, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-02-14 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X5V
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![BU of 5x5v by Molmil](/molmil-images/mine/5x5v) | Crystal structure of pseudorabies virus glycoprotein D | 分子名称: | GD | 著者 | Li, A, Lu, G, Qi, J, Wu, L, Tian, K, Luo, T, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2017-02-17 | 公開日 | 2017-04-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of pseudorabies virus glycoprotein D To Be Published
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5X5F
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![BU of 5x5f by Molmil](/molmil-images/mine/5x5f) | Prefusion structure of MERS-CoV spike glycoprotein, conformation 2 | 分子名称: | S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5GSR
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![BU of 5gsr by Molmil](/molmil-images/mine/5gsr) | Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide I5A | 分子名称: | 9-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-04-26 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
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5HGD
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![BU of 5hgd by Molmil](/molmil-images/mine/5hgd) | HLA*A2402 complexed with HIV nef138 Y2F mutant 10mer epitope | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2016-01-08 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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5YMW
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![BU of 5ymw by Molmil](/molmil-images/mine/5ymw) | Crystal structure of 8-mer peptide from Rous sarcoma virus in complex with BF2*1201 | 分子名称: | Beta-2-microglobulin, Class I histocompatibility antigen, F10 alpha chain, ... | 著者 | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | 登録日 | 2017-10-22 | 公開日 | 2018-10-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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5HGA
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![BU of 5hga by Molmil](/molmil-images/mine/5hga) | HLA*A2402 complex with HIV nef138 Y2F-8mer mutant epitope | 分子名称: | 8-mer from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2016-01-08 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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5GSX
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![BU of 5gsx by Molmil](/molmil-images/mine/5gsx) | Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-2 | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
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4F7P
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![BU of 4f7p by Molmil](/molmil-images/mine/4f7p) | Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. | 登録日 | 2012-05-16 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals. J.Virol., 86, 2012
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4MX1
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![BU of 4mx1 by Molmil](/molmil-images/mine/4mx1) | Structure of ricin A chain bound with 2-amino-4-oxo-N-(2-(3-phenylureido)ethyl)-3,4-dihydropteridine-7-carboxamide | 分子名称: | 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, MALONIC ACID, Ricin A chain, ... | 著者 | Robertus, J.D, Wiget, P.A, Manzano, L.A, Pruet, J.M, Gao, G, Saito, R, Jasheway, K.R, Monzingo, A.F, Anslyn, E.V. | 登録日 | 2013-09-25 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics. Bioorg.Med.Chem.Lett., 23, 2013
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4O2C
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![BU of 4o2c by Molmil](/molmil-images/mine/4o2c) | An Nt-acetylated peptide complexed with HLA-B*3901 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ... | 著者 | Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2013-12-17 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation J.Immunol., 192, 2014
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4K65
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![BU of 4k65 by Molmil](/molmil-images/mine/4k65) | Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | 著者 | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | 登録日 | 2013-04-15 | 公開日 | 2013-05-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
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4HX1
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![BU of 4hx1 by Molmil](/molmil-images/mine/4hx1) | Structure of HLA-A68 complexed with a tumor antigen derived peptide | 分子名称: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2012-11-09 | 公開日 | 2013-10-02 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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4HZW
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![BU of 4hzw by Molmil](/molmil-images/mine/4hzw) | Crystal structure of influenza A neuraminidase N3 complexed with laninamivir | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | 登録日 | 2012-11-15 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance. J.Virol., 87, 2013
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6II8
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![BU of 6ii8 by Molmil](/molmil-images/mine/6ii8) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L4B-18 Fab, Hemagglutinin, ... | 著者 | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2018-10-03 | 公開日 | 2018-10-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
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