7S26
 
 | | ROCK1 IN COMPLEX WITH LIGAND G5018 | | 分子名称: | 2-[methyl(phenyl)amino]-1-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethan-1-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Rho-associated protein kinase 1 | | 著者 | Ganichkin, O, Harris, S.F, Steinbacher, S. | | 登録日 | 2021-09-03 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.744 Å) | | 主引用文献 | Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors.
Nat Commun, 13, 2022
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7S25
 | | ROCK1 IN COMPLEX WITH LIGAND G4998 | | 分子名称: | 2-[3-(methoxymethyl)phenyl]-N-[4-(1H-pyrazol-4-yl)phenyl]acetamide, CHLORIDE ION, Rho-associated protein kinase 1 | | 著者 | Ganichkin, O, Harris, S.F, Steinbacher, S. | | 登録日 | 2021-09-03 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.337 Å) | | 主引用文献 | Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors.
Nat Commun, 13, 2022
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6S9A
 | | Artificial GTPase-BSE dimer of human Dynamin1 | | 分子名称: | CHLORIDE ION, Dynamin-1,Dynamin-1, ZINC ION | | 著者 | Ganichkin, O.M, Vancraenenbroeck, R, Rosenblum, G, Hofmann, H, Daumke, O, Noel, J.K. | | 登録日 | 2019-07-11 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7OFV
 | | NMR-guided design of potent and selective EphA4 agonistic ligands | | 分子名称: | ACETATE ION, EphA4 agonist ligand, Ephrin type-A receptor 4 | | 著者 | Ganichkin, O.M, Craig, T.K, Baggio, C, Pellecchia, M. | | 登録日 | 2021-05-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
J.Med.Chem., 64, 2021
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3BCA
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6TEO
 | | Crystal structure of a yeast Snu114-Prp8 complex | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | | 著者 | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | | 登録日 | 2019-11-12 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast.
Nucleic Acids Res., 48, 2020
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3BC8
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3BCB
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2V9V
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6EHN
 | | Structural insight into a promiscuous CE15 esterase from the marine bacterial metagenome | | 分子名称: | Carbohydrate esterase MZ0003, GLYCEROL | | 著者 | Helland, R, De Santi, C, Gani, O, Williamson, A.K. | | 登録日 | 2017-09-13 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insight into a CE15 esterase from the marine bacterial metagenome.
Sci Rep, 7, 2017
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3RG5
 | | Crystal Structure of Mouse tRNA(Sec) | | 分子名称: | ACETATE ION, GLYCEROL, SULFATE ION, ... | | 著者 | Wahl, M.C, Ganichkin, O.M, Anedchenko, E.A. | | 登録日 | 2011-04-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure analysis reveals functional flexibility in the selenocysteine-specific tRNA from mouse.
Plos One, 6, 2011
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