6VJC
 
 | | LmFPPS mutant T164Y in complex with 476A, IPP & Ca | | 分子名称: | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ... | | 著者 | Maheshwari, S, Kim, Y.S, Aripirala, S, Gabelli, S.B. | | 登録日 | 2020-01-15 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
|
|
6W7I
 | | LmFPPS mutant T164W in complex with 476A, IPP & Ca | | 分子名称: | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ... | | 著者 | Maheshwari, S, Kim, Y.S, Aripirala, S, Gabelli, S.B. | | 登録日 | 2020-03-19 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
|
|
6WW1
 | | Crystal structure of the LmFPPS mutant E97Y | | 分子名称: | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ... | | 著者 | Maheshwari, S, Kim, Y.S, Gabelli, S.B. | | 登録日 | 2020-05-07 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase.
Biochemistry, 59, 2020
|
|
3FZD
 | | Mutation of Asn28 disrupts the enzymatic activity and dimerization of SARS 3CLpro | | 分子名称: | 3C-like proteinase | | 著者 | Barrila, J, Gabelli, S, Bacha, U, Amzel, L.M, Freire, E. | | 登録日 | 2009-01-25 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) .
Biochemistry, 49, 2010
|
|
6AY0
 | | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) soaked with peptide | | 分子名称: | COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-09-07 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
6AMP
 | | Crystal structure of H172A PHM (CuH absent, CuM present) | | 分子名称: | COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-08-10 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
6AO6
 | | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) | | 分子名称: | COPPER (II) ION, GLYCEROL, NICKEL (II) ION, ... | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-08-15 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
6AN3
 | | Crystal structure of H172A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant soaked with peptide (no CuH bound, no peptide bound) | | 分子名称: | COPPER (II) ION, DI(HYDROXYETHYL)ETHER, Peptidyl-glycine alpha-amidating monooxygenase | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-08-11 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
3ID0
 | | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium | | 分子名称: | 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-19 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
3IBA
 | | Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+ | | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-15 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
3ICK
 | | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with minodronate and isopentenyl disphosphate | | 分子名称: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETIC ACID, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-17 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
3ICN
 | | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-Fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium | | 分子名称: | 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-17 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
3ICM
 | | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, Mg2+ and 1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium | | 分子名称: | 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-17 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
8E0W
 | | Crystal structure of mouse APCDD1 in P1 space group | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Hsieh, F.L, Chang, T.H, Gabelli, S.B, Nathans, J. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8E0R
 | | Crystal structure of mouse APCDD1 in P21 space group | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein APCDD1 | | 著者 | Hsieh, F.L, Chang, T.H, Gabelli, S.B, Nathans, J. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8FBY
 | |
8FCF
 | | Crystal structure of PLVAP CC1 in I212121 space group | | 分子名称: | Plasmalemma vesicle-associated protein | | 著者 | Chang, T.H, Hsieh, F.L, Gu, X, Kavran, J, Gabelli, S.B, Nathans, J. | | 登録日 | 2022-12-01 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-04-12 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
3EES
 | |
7KGU
 | | Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Miller, M.S, Aytenfisu, T.Y, Wright, K.M, Gabelli, S.B. | | 登録日 | 2020-10-18 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
|
|
6UUF
 | | Crystal structure of a Nudix Hydrolase from M. Smegmatis, RenU | | 分子名称: | Nudix Hydrolase, RenU | | 著者 | Wright, K.M, Yoder, J, Shoemaker, S, Hernandez, A, Iheanacho, A, Marques, I, Amzel, M.L, Gabelli, S.B. | | 登録日 | 2019-10-30 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of RenU
To Be Published
|
|
3EF5
 | |
3EEU
 | | Structure of the RNA pyrophosphohydrolase BdRppH in complex with Holmium | | 分子名称: | ACETATE ION, CHLORIDE ION, HOLMIUM ATOM, ... | | 著者 | Messing, S.A, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2008-09-05 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Biological Function of the RNA Pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus.
Structure, 17, 2009
|
|
4HFQ
 | | Crystal structure of UDP-X diphosphatase | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Duong-Ly, K.C, Amzel, L.M, Gabelli, S.B. | | 登録日 | 2012-10-05 | | 公開日 | 2013-08-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | A UDP-X diphosphatase from Streptococcus pneumoniae hydrolyzes precursors of peptidoglycan biosynthesis.
Plos One, 8, 2013
|
|
3FFU
 | |
3ICZ
 | | Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 1-(2,2-Bis-phosphono-ethyl)-3-butyl-pyridinium and isopentenyl pyrophosphate | | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 3-[(1E)-but-1-en-1-yl]-1-(2,2-diphosphonoethyl)pyridinium, Farnesyl pyrophosphate synthase, ... | | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | | 登録日 | 2009-07-19 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
|
|
