6YJY
| Crystal structure of human glutaminyl cyclase in complex with neurotensin 1-5 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTAMINE, Glutaminyl-peptide cyclotransferase, ... | Authors: | Funk, L.M, Sautner, V, Tittmann, K. | Deposit date: | 2020-04-05 | Release date: | 2020-07-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. Biochemistry, 59, 2020
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6HAF
| Pyruvate oxidase variant E59Q from L. plantarum in complex with phosphate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Funk, L.M, Sautner, V, Tittmann, K. | Deposit date: | 2018-08-07 | Release date: | 2019-08-21 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Low-barrier hydrogen bonds in enzyme cooperativity. Nature, 573, 2019
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7BBX
| Neisseria gonorrhoeae transaldolase, variant K8A | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Transaldolase | Authors: | Rabe von Pappenheim, F, Wensien, M, Funk, L.M, Tittmann, K. | Deposit date: | 2020-12-18 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function. Nature, 593, 2021
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