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PDB: 113 件

2QRT
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Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRS
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Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2R69
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Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
分子名称: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
著者Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
登録日2007-09-05
公開日2007-12-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
6N08
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Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-06
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.916 Å)
主引用文献Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
to be published
6MYM
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Crystal structure of hemagglutinin from influenza virus A/Phillipines/2/1982 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-01
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of hemagglutinin from influenza virus A/Phillipines/2/1982 (H3N2)
To be published
6MZK
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Crystal structure of hemagglutinin from influenza virus A/Pennsylvania/14/2010 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-05
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of hemagglutinin from influenza virus A/Pennsylvania/14/2010 (H3N2)
to be published
6MXU
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Crystal structure of hemagglutinin from influenza virus A/Texas/1/1977 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-10-31
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of hemagglutinin from influenza virus A/Texas/1/1977 (H3N2)
To be Published
6NK5
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Electron Cryo-Microscopy Of Chikungunya VLP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK7
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Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.99 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK6
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Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
1XAK
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STRUCTURE OF THE SARS-CORONAVIRUS ORF7A ACCESSORY PROTEIN
分子名称: SARS ORF7A ACCESSORY PROTEIN
著者Nelson, C.A, Lee, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2004-08-26
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein.
Structure, 13, 2005
1ZOX
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CLM-1 Mouse Myeloid Receptor Extracellular Domain
分子名称: CLM-1
著者Nelson, C.N, Burton, R.L, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-15
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Mouse CLM-1 Ectodomain
To be Published
1ZTX
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West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab
分子名称: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody
著者Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H.
登録日2005-05-27
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of West Nile virus neutralization by a therapeutic antibody.
Nature, 437, 2005
1F3J
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HISTOCOMPATIBILITY ANTIGEN I-AG7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, LYSOZYME C, ...
著者Latek, R.R, Unanue, E.R, Fremont, D.H.
登録日2000-06-04
公開日2000-09-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice.
Immunity, 12, 2000
1FNE
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HISTOCOMPATIBILITY ANTIGEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ...
著者Miley, M.J, Nelson, C.A, Fremont, D.H.
登録日2000-08-21
公開日2001-03-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional consequences of altering a peptide MHC anchor residue.
J.Immunol., 166, 2001
1FNG
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HISTOCOMPATIBILITY ANTIGEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ...
著者Miley, M.J, Nelson, C.A, Fremont, D.H.
登録日2000-08-21
公開日2001-03-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional consequences of altering a peptide MHC anchor residue.
J.Immunol., 166, 2001
7JX6
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STRUCTURE OF THE SARS-CoV-2 ORF8 ENCODED ACCESSORY PROTEIN
分子名称: ORF8 protein, SODIUM ION
著者Hall, P.D, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-08-26
公開日2020-09-23
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Crystal Structure of the SARS-CoV-2 ORF8 Protein
To Be Published
7K9J
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SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2H04 heavy chain, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9I
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SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, 2B04 light chain, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9K
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SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)
分子名称: 2H04 heavy chain, 2H04 light chain, Spike protein S1, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9H
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SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, ...
著者Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-29
公開日2021-09-29
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7KYL
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Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
分子名称: CHLORIDE ION, Envelope protein domain III, POWV-80 Fab heavy chain, ...
著者Errico, J.M, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-12-08
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
J.Exp.Med., 218, 2021
1PQZ
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MURINE CYTOMEGALOVIRUS IMMUNOMODULATORY PROTEIN M144
分子名称: Beta-2-microglobulin, MCMV M144
著者Miley, M.J, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2003-06-19
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MURINE CYTOMEGALOVIRUS IMMUNOMODULATORY PROTEIN M144
To be Published
1QTS
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CRYSTAL STRUCTURE OF THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE
分子名称: AP-2 CLATHRIN ADAPTOR ALPHA SUBUNIT (ALPHA-ADAPTIN C)
著者Traub, L.M, Downs, M.A, Westrich, J.L, Fremont, D.H.
登録日1999-06-29
公開日1999-07-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.
Proc.Natl.Acad.Sci.USA, 96, 1999
1R0D
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HIP1R THATCH DOMAIN CORE
分子名称: Huntingtin Interacting Protein 12
著者Brett, T.J, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2003-09-19
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural definition of the F-actin-binding THATCH domain from HIP1R
Nat.Struct.Mol.Biol., 13, 2006

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