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PDB: 3 results

1MS6
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BU of 1ms6 by Molmil
Dipeptide Nitrile Inhibitor Bound to Cathepsin S.
Descriptor: Cathepsin S, MORPHOLINE-4-CARBOXYLIC ACID [1S-(2-BENZYLOXY-1R-CYANO-ETHYLCARBAMOYL)-3-METHYL-BUTYL]AMIDE
Authors:Ward, Y.D, Thomson, D.S, Frye, L.L, Cywin, C.L, Morwick, T, Emmanuel, M.J, Zindell, R, McNeil, D, Bekkali, Y, Giradot, M, Hrapchak, M, DeTuri, M, Crane, K, White, D, Pav, S, Wang, Y, Hao, M.H, Grygon, C.A, Labadia, M.E, Freeman, D.M, Davidson, W, Hopkins, J.L, Brown, M.L, Spero, D.M.
Deposit date:2002-09-19
Release date:2003-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors
J.Med.Chem., 45, 2002
4WXS
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Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain
Descriptor: CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:Donegan, R.K, Freeman, D.M, Lieberman, R.L.
Deposit date:2014-11-14
Release date:2015-04-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for misfolding in myocilin-associated glaucoma.
Hum.Mol.Genet., 24, 2015
4WXU
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BU of 4wxu by Molmil
Crystal Structure of the Selenomthionine Incorporated Myocilin Olfactomedin Domain E396D Variant.
Descriptor: CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:Donegan, R.K, Freeman, D.M, Lieberman, R.L.
Deposit date:2014-11-14
Release date:2015-04-01
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Structural basis for misfolding in myocilin-associated glaucoma.
Hum.Mol.Genet., 24, 2015

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