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PDB: 158 results
2V1O
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BU of 2v1o by Molmil
Crystal structure of N-terminal domain of acyl-CoA thioesterase 7
Descriptor: COENZYME A, CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE
Authors:Forwood, J.K, Thakur, A.S, Guncar, G, Marfori, M, Mouradov, D, Meng, W.N, Robinson, J, Huber, T, Kellie, S, Martin, J.L, Hume, D.A, Kobe, B.
Deposit date:2007-05-28
Release date:2007-06-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-Coa Thioesterase 7 and its Role in Inflammation.
Proc.Natl.Acad.Sci.USA, 104, 2007
3EA5
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BU of 3ea5 by Molmil
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
Authors:Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
Deposit date:2008-08-24
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
6RPK
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BU of 6rpk by Molmil
non-expanded bat circovirus with DNA VLP
Descriptor: Capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:non-expanded bat circovirus with DNA VLP
To Be Published
6RPO
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BU of 6rpo by Molmil
bat circovirus without DNA VLP
Descriptor: bat circovirus capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:bat circovirus without DNA VLP
To Be Published
6RPL
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BU of 6rpl by Molmil
Expanded bat circovirus with DNA VLP
Descriptor: Capsid protein
Authors:Forwood, J.K, Luque, D, Mata, C.P, Das, S, Raidal, S.
Deposit date:2019-05-14
Release date:2020-11-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:expanded bat circovirus with DNA VLP
To Be Published
3ND2
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BU of 3nd2 by Molmil
Structure of Yeast Importin-beta (Kap95p)
Descriptor: Importin subunit beta-1
Authors:Forwood, J.K, Kobe, B.
Deposit date:2010-06-06
Release date:2010-07-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
6UDS
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BU of 6uds by Molmil
Crystal structure of a putative 3-oxoacyl-ACP reductase (FabG) from Acinetobacter baumannii
Descriptor: 3-oxoacyl-(Acyl-carrier-protein) reductase
Authors:Forwood, J.K, Cross, E.M.
Deposit date:2019-09-19
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
7JVO
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BU of 7jvo by Molmil
Importin alpha bound to the C-terminus of ACE2
Descriptor: ARG-LYS-LYS-LYS-ASN-LYS-ALA, Importin subunit alpha-1
Authors:Forwood, J.K, Cross, E.M, Tsimbalyuk, S.
Deposit date:2020-08-22
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication.
Cell Discov, 7, 2021
3SPS
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BU of 3sps by Molmil
Crystal Structure of Apo-Hexameric Acyl-CoA Thioesterase
Descriptor: Acyl-CoA hydrolase
Authors:Forwood, J.K, Marfori, M, Kobe, B.
Deposit date:2011-07-03
Release date:2011-08-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-Induced Conformational Changes within a Hexameric Acyl-CoA Thioesterase
To be Published
8ECH
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BU of 8ech by Molmil
Tick-borne encephalitis virus capsid protein NLS bound to host importin alpha 2
Descriptor: Capsid protein C, Importin subunit alpha-1
Authors:Roby, J.A, Forwood, J.K.
Deposit date:2022-09-02
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and biological functions of tick-borne encephalitis virus capsid protein
To Be Published
4YLT
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BU of 4ylt by Molmil
Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Yersinia pestis
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 3
Authors:Nanson, J.D, Forwood, J.K.
Deposit date:2015-03-05
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
Sci Rep, 5, 2015
7N8J
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BU of 7n8j by Molmil
Human importin alpha 1 in complex with Bimax2 peptide
Descriptor: BIMAX2, Importin subunit alpha-1
Authors:Donnelly, C.M, Cross, E.M, Tsimbalyuk, S, Forwood, J.K.
Deposit date:2021-06-15
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Human importin alpha 1:Bimax2 peptide complex
To Be Published
5W41
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BU of 5w41 by Molmil
Zika MR766 NLS in complex with Importin alpha subunit-1
Descriptor: Importin subunit alpha-1, ZIKA MR766 NLS
Authors:Jeffress, S, Smith, K.M, Forwood, J.K.
Deposit date:2017-06-08
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells.
ACS Infect Dis, 2019
5HWF
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BU of 5hwf by Molmil
The structural and biochemical characterization of acyl-coa hydrolase mutant Asn28Ala from Staphylococcus aureus.
Descriptor: Thioesterase
Authors:Khandokar, Y.B, Srivastava, P.S, Forwood, J.K.
Deposit date:2016-01-29
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus
To Be Published
8VPU
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BU of 8vpu by Molmil
Crystal structure of mouse Importin alpha in complex with dengue virus 3 NS5 central NLS peptide
Descriptor: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 central NLS peptide
Authors:Roman, N, Swarbrick, C.M.D, Forwood, J.K.
Deposit date:2024-01-17
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization.
Acs Infect Dis., 10, 2024
8Q8K
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BU of 8q8k by Molmil
KI Polyomavirus LTA NLS bound to importin alpha 2
Descriptor: Importin subunit alpha-1, Large T antigen
Authors:Cross, E.M, Forwood, J.K, Alvisi, G.
Deposit date:2023-08-18
Release date:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
8QXX
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BU of 8qxx by Molmil
HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2
Descriptor: DNA polymerase processivity factor, Importin subunit alpha-1
Authors:Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G.
Deposit date:2023-10-25
Release date:2023-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
8QXW
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BU of 8qxw by Molmil
HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2
Descriptor: DNA polymerase processivity factor, Importin subunit alpha-1
Authors:Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G.
Deposit date:2023-10-25
Release date:2023-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
6WX9
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BU of 6wx9 by Molmil
SOX2 bound to Importin-alpha 5
Descriptor: Importin subunit alpha-5, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-10
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WPR
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BU of 6wpr by Molmil
Crystal structure of a putative 3-oxoacyl-ACP reductase (FabG) with NADP(H) from Acinetobacter baumannii
Descriptor: 3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cross, E.M, Forwood, J.K.
Deposit date:2020-04-27
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
8G8Q
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BU of 8g8q by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:p52 monopartite NLS in complex with Importin alpha 2
To Be Published
8G8R
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BU of 8g8r by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:monopartite p52 NLS in complex with Importin alpha 2
To Be Published
8G8S
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BU of 8g8s by Molmil
bipartite p52 NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:p52 bipartite NLS in complex with Importin alpha 2
To Be Published
5KLT
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BU of 5klt by Molmil
Prototypical P4[M]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[M]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
5KLR
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BU of 5klr by Molmil
Prototypical P4[R]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[R]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018

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PDB entries from 2024-08-21

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