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PDB: 2 results

4IGH
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BU of 4igh by Molmil
High resolution crystal structure of human dihydroorotate dehydrogenase bound with 4-quinoline carboxylic acid analog
Descriptor: 3-[decyl(dimethyl)ammonio]propane-1-sulfonate, 6-fluoro-2-[2-methyl-4-phenoxy-5-(propan-2-yl)phenyl]quinoline-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), ...
Authors:Deng, X, Das, P, Fontoura, B.M.A, Phillips, M.A, De Brabander, J.K.
Deposit date:2012-12-17
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:SAR Based Optimization of a 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity.
ACS MED.CHEM.LETT., 4, 2013
6N3H
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BU of 6n3h by Molmil
Crystal structure of Kelch domain of the human NS1 binding protein
Descriptor: Influenza virus NS1A-binding protein
Authors:Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M.
Deposit date:2018-11-15
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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