9I68
 
 | | Crystal structure of human Cdc20 bound to synthetic D-box peptide D21 | | Descriptor: | ARG-ALA-PRO-3EG-SER-ASP, Cell division cycle protein 20 homolog | | Authors: | Eapen, R, Okoye, C, Stubbs, C, Schimpl, M, Tischer, T, Fisher, E.J, Zacharopoulou, M, Ferrer, F, Barford, D, Spring, D, Lindon, C, Phillips, C, Itzhaki, L.S. | | Deposit date: | 2025-01-29 | | Release date: | 2025-02-12 | | Method: | X-RAY DIFFRACTION (1.505 Å) | | Cite: | Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
To be published
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9I69
 | | Crystal structure of human Cdc20 bound to synthetic D-box peptide D20 | | Descriptor: | ARG-ALA-PRO-0JY-SER-ASP, Cell division cycle protein 20 homolog | | Authors: | Eapen, R, Okoye, C, Stubbs, C, Schimpl, M, Tischer, T, Fisher, E.J, Zacharopoulou, M, Ferrer, F, Barford, D, Spring, D, Lindon, C, Phillips, C, Itzhaki, L.S. | | Deposit date: | 2025-01-29 | | Release date: | 2025-02-12 | | Method: | X-RAY DIFFRACTION (1.463 Å) | | Cite: | Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
To be published
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9I6A
 | | Crystal structure of human Cdc20 bound to synthetic D-box peptide D7 | | Descriptor: | ALA-PRO-0JY-GLY, Cell division cycle protein 20 homolog | | Authors: | Eapen, R, Okoye, C, Stubbs, C, Schimpl, M, Tischer, T, Fisher, E.J, Zacharopoulou, M, Ferrer, F, Barford, D, Spring, D, Lindon, C, Phillips, C, Itzhaki, L.S. | | Deposit date: | 2025-01-29 | | Release date: | 2025-02-12 | | Method: | X-RAY DIFFRACTION (1.915 Å) | | Cite: | Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
To be published
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2VV9
 | | CDK2 in complex with an imidazole piperazine | | Descriptor: | 2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol, CELL DIVISION PROTEIN KINASE 2 | | Authors: | Acton, D.G, Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Finlay, M.R, Fisher, E, Gerhardt, S, Graham, M.A, Green, C.P, Heaton, D.W, Loddick, S.A, Morgentin, R, Read, J, Roberts, A, Stanway, J, Tucker, J.A, Weir, H.M. | | Deposit date: | 2008-06-04 | | Release date: | 2008-08-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Imidazole Piperazines: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors with a Novel Binding Mode.
Bioorg.Med.Chem.Lett., 18, 2008
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2W05
 | | Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5b | | Descriptor: | CELL DIVISION PROTEIN KINASE 2, N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE | | Authors: | Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Breed, J, Byth, K.F, Culshaw, J.D, Finlay, M.R, Fisher, E, Green, C.P, Heaton, D.W, Nash, I.A, Newcombe, N.J, Oakes, S.E, Pauptit, R.A, Roberts, A, Stanway, J.J, Thomas, A.P, Tucker, J.A, Weir, H.M. | | Deposit date: | 2008-08-08 | | Release date: | 2008-10-14 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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2W06
 | | Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5c | | Descriptor: | 4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | | Authors: | Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Byth, K.F, Culshaw, J.D, Finlay, M.R.V, Fisher, E, Mcmiken, H.H.J, Green, C.P, Heaton, D.W, Nash, I.A, Newcombe, N.J, Oakes, S.E, Roberts, A, Stanway, J.J, Thomas, A.P, Tucker, J.A, Weir, H.M. | | Deposit date: | 2008-08-08 | | Release date: | 2008-09-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
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