4BOH
| Madanins (MEROPS I53) are cleaved by thrombin and factor Xa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, SULFATE ION, ... | Authors: | Figueiredo, A.C, deSanctis, D, Pereira, P.J.B. | Deposit date: | 2013-05-20 | Release date: | 2013-09-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | The Tick-Derived Anticoagulant Madanin is Processed by Thrombin and Factor Xa. Plos One, 8, 2013
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2K0D
| NMR structure of a mutant colicin e7 immunity protein im7 with an extended helix III | Descriptor: | Colicin-E7 immunity protein | Authors: | Figueiredo, A.M, Whittaker, S.B, Knowling, S.E, Spronk, C.A, Radford, S.E, Moore, G.R. | Deposit date: | 2008-02-01 | Release date: | 2009-01-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Amino acid insertion reveals a necessary three-helical intermediate in the folding pathway of the colicin E7 immunity protein Im7. J.Mol.Biol., 392, 2009
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3U69
| Unliganded wild-type human thrombin | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Barbosa Pereira, P.J. | Deposit date: | 2011-10-12 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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4E05
| Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | Authors: | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | Deposit date: | 2012-03-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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4E06
| Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | Authors: | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | Deposit date: | 2012-03-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.196 Å) | Cite: | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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3U8T
| Human thrombin complexed with D-Phe-Pro-D-Arg-Cys | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | Deposit date: | 2011-10-17 | Release date: | 2012-04-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.861 Å) | Cite: | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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3U8O
| Human thrombin complexed with D-Phe-Pro-D-Arg-D-Thr | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | Deposit date: | 2011-10-17 | Release date: | 2012-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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3U8R
| Human thrombin complexed with D-Phe-Pro-D-Arg-Ile | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | Deposit date: | 2011-10-17 | Release date: | 2012-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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5NFG
| Structure of recombinant cardosin B from Cynara cardunculus | Descriptor: | Procardosin-B,Procardosin-B, alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Pereira, P.J.B, Figueiredo, A.C, Manso, J.A, Almeida, C.M, Simoes, I. | Deposit date: | 2017-03-14 | Release date: | 2017-10-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.375 Å) | Cite: | Functional and structural characterization of synthetic cardosin B-derived rennet. Appl. Microbiol. Biotechnol., 101, 2017
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6QYT
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A truncated analogue | Descriptor: | DAL-LEU-SER-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYS
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Nisin Ring B | Descriptor: | DBB-PRO-GLY-CYS-LYS | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QTF
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, major conformer | Descriptor: | DCY-LEU-GLY-ALA-THR | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-02-25 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYU
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A | Descriptor: | PHE-DHA-DAL-LEU-DHA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QM1
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Nisin Ring B (Lan8,11) analogue | Descriptor: | DAL-PRO-GLY-CYS-LYS | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-02-01 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYR
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, minor conformer | Descriptor: | DAL-LEU-GLY-CYS-THR | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYW
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - nisin ring A | Descriptor: | ILE-DBU-DAL-ILE-DHA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYV
| Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A (Ser2, Ala5, Ala8) analogue | Descriptor: | PHE-SER-DAL-LEU-ALA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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