6YPT
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1ZY1
| X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A) in complex with Met-Ala-Ser | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION, ... | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | 登録日 | 2005-06-09 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
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5JF8
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor RAS358 (21) | 分子名称: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5MTC
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
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5MTD
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
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4JE7
| Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | 分子名称: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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4JE6
| Crystal structure of a human-like mitochondrial peptide deformylase | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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5JF4
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT019 | 分子名称: | (3R)-3-{3-[(1-benzofuran-3-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JF5
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT020 | 分子名称: | (3R)-3-{3-[(2H-1,3-benzodioxol-5-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JF2
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT002 | 分子名称: | (3R)-3-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-N-hydroxyheptanamide, ACETATE ION, IMIDAZOLE, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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4JE8
| Crystal structure of a human-like mitochondrial peptide deformylase in complex with Met-Ala-Ser | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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5JF1
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with actinonin | 分子名称: | ACETATE ION, ACTINONIN, Peptide deformylase, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JEX
| Crystal structure of type 2 PDF from Streptococcus agalactiae, crystallized in imidazole buffer | 分子名称: | IMIDAZOLE, Peptide deformylase, ZINC ION | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JF3
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT018 | 分子名称: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JEY
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5JF6
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor 6b (AB47) | 分子名称: | 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ACETATE ION, Peptide deformylase, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JEZ
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Ser | 分子名称: | ACETATE ION, Met-Ala-Ser, Peptide deformylase, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5JF7
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor SMP289 | 分子名称: | 2-(3-benzyl-5-bromo-1H-indol-1-yl)-N-hydroxyacetamide, ACETATE ION, IMIDAZOLE, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5MTE
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T in complex with actinonin - crystal form II | 分子名称: | ACTINONIN, NICKEL (II) ION, Putative uncharacterized protein orf60T, ... | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-11-29 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts. Biochim. Biophys. Acta, 1866, 2018
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5JF0
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Arg | 分子名称: | ACETATE ION, MET-ALA-ARG, NICKEL (II) ION, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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3M6P
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3O3J
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3M6Q
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3M6O
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3PN4
| Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with actinonin (crystallized in PEG-550-MME) | 分子名称: | ACTINONIN, Peptide deformylase 1B, chloroplastic, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2010-11-18 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis. Plos Biol., 9, 2011
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