6YQY
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![BU of 6yqy by Molmil](/molmil-images/mine/6yqy) | Crystal structure of sTIM11noCys, a de novo designed TIM barrel | Descriptor: | de novo designed TIM barrel sTIM11noCys | Authors: | Romero-Romero, S, Wiese, G.J, Kordes, S, Shanmugaratnam, S, Fernandez-Velasco, D.A, Hocker, B. | Deposit date: | 2020-04-18 | Release date: | 2021-07-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.876 Å) | Cite: | The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
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6YQX
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![BU of 6yqx by Molmil](/molmil-images/mine/6yqx) | Crystal structure of DeNovoTIM13, a de novo designed TIM barrel | Descriptor: | CHLORIDE ION, GLYCEROL, de novo designed TIM barrel DeNovoTIM13 | Authors: | Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Fernandez-Velasco, D.A, Hocker, B. | Deposit date: | 2020-04-18 | Release date: | 2021-07-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.638 Å) | Cite: | The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
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6Z2I
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![BU of 6z2i by Molmil](/molmil-images/mine/6z2i) | Crystal structure of DeNovoTIM6, a de novo designed TIM barrel | Descriptor: | de novo designed TIM barrel DeNovoTIM6 | Authors: | Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Rodriguez-Romero, A, Fernandez-Velasco, D.A, Hocker, B. | Deposit date: | 2020-05-15 | Release date: | 2021-07-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
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4AJ0
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![BU of 4aj0 by Molmil](/molmil-images/mine/4aj0) | Crystallographic structure of an amyloidogenic variant, 3rCW, of the germinal line lambda 3 | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, ACETATE ION, GERMINAL LINE LAMBDA 3 3RCW VARIANT | Authors: | Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B. | Deposit date: | 2012-02-15 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains. J.Biol.Chem., 290, 2015
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4AIZ
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![BU of 4aiz by Molmil](/molmil-images/mine/4aiz) | Crystallographic structure of 3mJL2 from the germinal line lambda 3 | Descriptor: | 1,5:6,10-dianhydro-3,4,7,8-tetradeoxy-2,9-bis-C-(hydroxymethyl)-L-manno-decitol, CITRIC ACID, SULFATE ION, ... | Authors: | Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B. | Deposit date: | 2012-02-15 | Release date: | 2013-03-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains. J.Biol.Chem., 290, 2015
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4AIX
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![BU of 4aix by Molmil](/molmil-images/mine/4aix) | Crystallographic structure of an amyloidogenic variant, 3rC34Y, of the germinal line lambda 3 | Descriptor: | IG LAMBDA CHAIN V-IV REGION BAU | Authors: | Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B. | Deposit date: | 2012-02-15 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains. J.Biol.Chem., 290, 2015
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1M6J
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![BU of 1m6j by Molmil](/molmil-images/mine/1m6j) | |
6CG9
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![BU of 6cg9 by Molmil](/molmil-images/mine/6cg9) | Crystal structure of Triosephosphate Isomerase from Zea mays (mexican corn) | Descriptor: | ACETATE ION, GLYCEROL, Triosephosphate isomerase, ... | Authors: | Romero-Romero, S, Fernandez-Velasco, D.A, Rodriguez-Romero, A. | Deposit date: | 2018-02-19 | Release date: | 2018-10-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and conformational stability of the triosephosphate isomerase from Zea mays. Comparison with the chemical unfolding pathways of other eukaryotic TIMs. Arch. Biochem. Biophys., 658, 2018
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6WVS
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![BU of 6wvs by Molmil](/molmil-images/mine/6wvs) | Hyperstable de novo TIM barrel variant DeNovoTIM15 | Descriptor: | DeNovoTIM15 hyperstable de novo TIM barrel | Authors: | Bick, M.J, Haydon, I.C, Caldwell, S.J, Zeymer, C, Huang, P, Fernandez-Velasco, D.A, Baker, D. | Deposit date: | 2020-05-06 | Release date: | 2020-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117, 2020
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6NEE
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![BU of 6nee by Molmil](/molmil-images/mine/6nee) | |
4Y9A
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![BU of 4y9a by Molmil](/molmil-images/mine/4y9a) | |
4Y8F
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![BU of 4y8f by Molmil](/molmil-images/mine/4y8f) | |
4Y96
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![BU of 4y96 by Molmil](/molmil-images/mine/4y96) | Crystal structure of Triosephosphate Isomerase from Gemmata obscuriglobus | Descriptor: | CALCIUM ION, PHOSPHATE ION, SODIUM ION, ... | Authors: | Romero-Romero, S, Rodriguez-Romero, A, Fernandez-Velasco, D.A. | Deposit date: | 2015-02-17 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.581 Å) | Cite: | Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins. Phys Chem Chem Phys, 17, 2015
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