5M1S
| Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode | 分子名称: | DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2016-10-10 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Self-correcting mismatches during high-fidelity DNA replication. Nat. Struct. Mol. Biol., 24, 2017
|
|
3OB8
| Structure of the beta-galactosidase from Kluyveromyces lactis in complex with galactose | 分子名称: | Beta-galactosidase, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | 登録日 | 2010-08-06 | 公開日 | 2011-08-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase. J.Struct.Biol., 177, 2012
|
|
3OBA
| Structure of the beta-galactosidase from Kluyveromyces lactis | 分子名称: | Beta-galactosidase, GLYCEROL, MANGANESE (III) ION | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | 登録日 | 2010-08-06 | 公開日 | 2011-08-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase. J.Struct.Biol., 177, 2012
|
|
3LRK
| Structure of alfa-galactosidase (MEL1) from Saccharomyces cerevisiae | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | 登録日 | 2010-02-11 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases. J.Biol.Chem., 285, 2010
|
|
3LRM
| Structure of alfa-galactosidase from Saccharomyces cerevisiae with raffinose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | 登録日 | 2010-02-11 | 公開日 | 2010-06-30 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases. J.Biol.Chem., 285, 2010
|
|
3LRL
| Structure of alfa-galactosidase (MEL1) from Saccharomyces cerevisiae with melibiose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | 登録日 | 2010-02-11 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases. J.Biol.Chem., 285, 2010
|
|
5FKU
| cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA polymerase III alpha, beta, epsilon, tau complex) | 分子名称: | DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2015-10-20 | 公開日 | 2015-11-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.34 Å) | 主引用文献 | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
|
|
5FKV
| cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex) | 分子名称: | DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2015-10-20 | 公開日 | 2015-11-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.04 Å) | 主引用文献 | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
|
|
5FKW
| cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon) | 分子名称: | DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2015-10-20 | 公開日 | 2015-11-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
|
|
7AI7
| MutS in Intermediate state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*TP*TP*AP*GP*CP*TP*TP*AP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*TP*AP*AP*CP*TP*AP*AP*G)-3'), ... | 著者 | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | 登録日 | 2020-09-26 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
7AIB
| MutS-MutL in clamp state | 分子名称: | DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ... | 著者 | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | 登録日 | 2020-09-26 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
7AI6
| MutS in mismatch bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein MutS | 著者 | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | 登録日 | 2020-09-26 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
7AI5
| MutS in Scanning state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*AP*AP*TP*TP*CP*GP*CP*CP*CP*TP*AP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*TP*AP*GP*GP*GP*CP*GP*AP*AP*TP*TP*GP*GP*GP*TP*AP*CP*CP*G)-3'), ... | 著者 | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | 登録日 | 2020-09-26 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
7AIC
| MutS-MutL in clamp state (kinked clamp domain) | 分子名称: | DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ... | 著者 | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | 登録日 | 2020-09-26 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
5IDE
| Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model I) | 分子名称: | Glutamate receptor 2, Glutamate receptor 3 | 著者 | Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H. | 登録日 | 2016-02-24 | 公開日 | 2016-03-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.25 Å) | 主引用文献 | Structure and organization of heteromeric AMPA-type glutamate receptors. Science, 352, 2016
|
|
5IDF
| Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model II) | 分子名称: | Glutamate receptor 2, Glutamate receptor 3 | 著者 | Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H. | 登録日 | 2016-02-24 | 公開日 | 2016-03-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (10.31 Å) | 主引用文献 | Structure and organization of heteromeric AMPA-type glutamate receptors. Science, 352, 2016
|
|
6S6Z
| Structure of beta-Galactosidase from Thermotoga maritima | 分子名称: | Beta-galactosidase, MAGNESIUM ION | 著者 | Miguez-Amil, S, Jimenez-Ortega, E, Ramirez Escudero, M, Sanz-Aparicio, J, Fernandez-Leiro, R. | 登録日 | 2019-07-04 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering. Acs Chem.Biol., 15, 2020
|
|
7AS4
| Recombinant human gTuRC | 分子名称: | Actin, cytoplasmic 1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Serna, M, Fernandez-Leiro, R, Llorca, O. | 登録日 | 2020-10-26 | 公開日 | 2021-01-20 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase. Sci Adv, 6, 2020
|
|
7P6X
| Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | 著者 | Llorca, O, Serna, M, Fernandez-Leiro, R. | 登録日 | 2021-07-18 | 公開日 | 2021-12-15 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8. Nucleic Acids Res., 50, 2022
|
|
8Q62
| Early closed conformation of the g-tubulin ring complex | 分子名称: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... | 著者 | Llorca, O, Serna, M, Fernandez-Leiro, R. | 登録日 | 2023-08-10 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation. Science, 383, 2024
|
|