4IMK
 
 | | Uncrossed Fab binding to human Angiopoietin 2 | | Descriptor: | GLYCEROL, Heavy Chain, Light Chain, ... | | Authors: | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | | Deposit date: | 2013-01-03 | | Release date: | 2013-04-17 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (2.202 Å) | | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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4IML
 | | CrossFab binding to human Angiopoietin 2 | | Descriptor: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | | Authors: | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | | Deposit date: | 2013-01-03 | | Release date: | 2013-04-17 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (2.931 Å) | | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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3QB0
 | | Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION | | Authors: | Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. | | Deposit date: | 2011-01-12 | | Release date: | 2011-05-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.404 Å) | | Cite: | Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin.
Embo J., 30, 2011
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6T9E
 | | Crystal structure of a bispecific DutaFab in complex with human PDGF | | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | | Deposit date: | 2019-10-28 | | Release date: | 2020-12-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.989 Å) | | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
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6T9D
 | | Crystal structure of a bispecific DutaFab in complex with human VEGF121 | | Descriptor: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | | Deposit date: | 2019-10-28 | | Release date: | 2020-12-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.905 Å) | | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
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2JZX
 | | PCBP2 KH1-KH2 domains | | Descriptor: | Poly(rC)-binding protein 2 | | Authors: | Du, Z, Fenn, S, Tjhen, R, James, T. | | Deposit date: | 2008-01-21 | | Release date: | 2008-08-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the first and second KH domains of human poly-C binding protein-2 reveals insights into its regulatory mechanisms
To be Published
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2P2R
 | | Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA | | Descriptor: | 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 | | Authors: | James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. | | Deposit date: | 2007-03-07 | | Release date: | 2007-06-12 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution.
Nucleic Acids Res., 35, 2007
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1K8L
 | | XBY6: An analog of CK14 containing 6 dithiophosphate groups | | Descriptor: | FIRST STRAND OF CK14 DNA DUPLEX, SECOND STRAND OF CK14 DNA DUPLEX | | Authors: | Volk, D.E, Yang, X, Fennewald, S.M, King, D.J, Bassett, S.E, Venkitachalam, S, Herzog, N, Luxon, B.A, Gorenstein, D.G. | | Deposit date: | 2001-10-24 | | Release date: | 2003-04-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB
Bioorg.Chem., 30, 2002
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1K8J
 | | NMR STRUCTURE OF THE CK14 DNA DUPLEX: A PORTION OF THE KNOWN NF-kB SEQUENCE CK1 | | Descriptor: | FIRST STRAND OF CK14 DNA DUPLEX, SECOND STRAND OF CK14 DNA DUPLEX | | Authors: | Volk, D.E, Yang, X, Fennewald, S.M, King, D.J, Bassett, S.E, Venkitachalam, S, Herzog, N, Luxon, B.A, Gorenstein, D.G. | | Deposit date: | 2001-10-24 | | Release date: | 2003-04-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB
Bioorg.Chem., 30, 2002
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1K8N
 | | NMR structure of the XBY2 DNA duplex, an analog of CK14 containing phosphorodithioate groups at C22 and C24 | | Descriptor: | FIRST STRAND OF CK14 DNA DUPLEX, SECOND STRAND OF CK14 DNA DUPLEX | | Authors: | Volk, D.E, Yang, X, Fennewald, S.M, King, D.J, Bassett, S.E, Venkitachalam, S, Herzog, N, Luxon, B.A, Gorenstein, D.G. | | Deposit date: | 2001-10-24 | | Release date: | 2003-04-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB
Bioorg.Chem., 30, 2002
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