7X0M
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7X0N
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7X0J
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8I22
| Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | 分子名称: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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8I35
| Acyl-ACP synthetase structure bound to oleic acid | 分子名称: | Acyl-acyl carrier protein synthetase, OLEIC ACID | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to oleic acid To Be Published
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8I51
| Acyl-ACP synthetase structure bound to AMP-MC7 | 分子名称: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-21 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-MC7 To Be Published
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8I3I
| Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 | 分子名称: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-17 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 To Be Published
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8I6M
| Acyl-ACP synthetase structure bound to AMP-C18:1 | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-28 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-C18:1 To Be Published
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8HZX
| Acyl-ACP synthetase structure-2 | 分子名称: | Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-09 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Acyl-ACP synthetase structure-2 To Be Published
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8I49
| Acyl-ACP synthetase structure bound to ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-18 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to ATP. To Be Published
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2FOX
| CLOSTRIDIUM BEIJERINCKII FLAVODOXIN: SEMIQUINONE | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1997-01-08 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
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7WE6
| Structure of Csy-AcrIF24-dsDNA | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-12-22 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
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3QCS
| Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-[2-Amino-6-(4-morpholinyl)-4-pyrimidinyl]-1H-indazol-3-amine | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, 6-[2-amino-6-(morpholin-4-yl)pyrimidin-4-yl]-2H-indazol-3-amine, GLYCEROL, ... | 著者 | Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M. | 登録日 | 2011-01-17 | 公開日 | 2011-03-09 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.487 Å) | 主引用文献 | Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors. J.Med.Chem., 54, 2011
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3QD0
| Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with (2R,5S)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide | 分子名称: | (3S,6R)-1-[2-amino-6-(3-amino-2H-indazol-6-yl)pyrimidin-4-yl]-6-methyl-N-phenylpiperidine-3-carboxamide, 3-phosphoinositide-dependent protein kinase 1, GLYCEROL, ... | 著者 | Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M. | 登録日 | 2011-01-17 | 公開日 | 2011-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors. J.Med.Chem., 54, 2011
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6K81
| Crystal structure of human VASH1-SVBP complex | 分子名称: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | 著者 | Liu, X, Wang, H, Zhang, Y, Feng, Y. | 登録日 | 2019-06-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural insights into tubulin detyrosination by vasohibins-SVBP complex. Cell Discov, 5, 2019
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8HOO
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8HOT
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8I23
| Clostridium thermocellum RNA polymerase transcription open complex with SigI1 and its promoter | 分子名称: | DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. | 登録日 | 2023-01-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structure of the transcription open complex of distinct sigma I factors. Nat Commun, 14, 2023
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8I24
| Clostridium thermocellum RNA polymerase transcription open complex with SigI6 and its promoter | 分子名称: | DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. | 登録日 | 2023-01-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Structure of the transcription open complex of distinct sigma I factors. Nat Commun, 14, 2023
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7CGW
| Complex structure of PD-1 and tislelizumab Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of tislelizumab Fab, Light chain of tislelizumab Fab, ... | 著者 | Hong, Y, Feng, Y.C, Liu, Y. | 登録日 | 2020-07-02 | 公開日 | 2021-04-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage. Febs Open Bio, 11, 2021
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6L87
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6IH3
| Crystal structure of Phosphite Dehydrogenase from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide | 分子名称: | Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Song, X, Feng, Y, Zhao, Z, Liu, Y. | 登録日 | 2018-09-28 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.942 Å) | 主引用文献 | Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor Acs Catalysis, 9, 2019
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6IH8
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6IVU
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6IVS
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