1IGM
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1B2W
| COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | Descriptor: | PROTEIN (ANTIBODY (HEAVY CHAIN)), PROTEIN (ANTIBODY (LIGHT CHAIN)) | Authors: | Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasquez, M, Queen, C, Ramsland, P.A, Edmundson, A.B. | Deposit date: | 1998-12-01 | Release date: | 1999-05-06 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody. J.Mol.Recog., 12, 1999
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1B4J
| COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | Descriptor: | ANTIBODY | Authors: | Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasques, M, Queen, C, Ramsland, P.A, Edmundson, A.B. | Deposit date: | 1998-12-22 | Release date: | 1999-06-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody. J.Mol.Recog., 12, 1999
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5W7O
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5WJR
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7U87
| Product of 13mer primer with activated G monomer diastereomer 1 | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3') | Authors: | Fang, Z, Szostak, J.W. | Deposit date: | 2022-03-08 | Release date: | 2023-03-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U88
| Product of 13mer primer with activated G monomer diastereomer 2 | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3'), SULFATE ION | Authors: | Fang, Z, Szostak, J.W. | Deposit date: | 2022-03-08 | Release date: | 2023-03-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U89
| Product of 14mer primer with activated G monomer diastereomer 1 | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3') | Authors: | Fang, Z, Szostak, J.W. | Deposit date: | 2022-03-08 | Release date: | 2023-03-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U8A
| Product of 14mer primer with activated G monomer diastereomer 2 | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3') | Authors: | Fang, Z, Szostak, J.W. | Deposit date: | 2022-03-08 | Release date: | 2023-03-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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4TS3
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7U8B
| Product of 14mer primer with activated asymmetric GA dimer diastereomer 1 | Descriptor: | 5'-O-[(S)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]adenosine, RNA (5'-R(*(TLN)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3'), SULFATE ION | Authors: | Fang, Z, Szostak, J.W. | Deposit date: | 2022-03-08 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Understanding the metal ion function in the RNA non-enzymatic extesion with phosphorothioates To Be Published
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6F52
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6F4W
| Crystal structure of H. pylori purine nucleoside phosphorylase in complex with formycin A | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-11-30 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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6F5I
| Crystal structure of H. pylori purine nucleoside phosphorylase | Descriptor: | METHANOL, Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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6F5A
| Crystal structure of H. pylori purine nucleoside phosphorylase | Descriptor: | Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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8FER
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8FEO
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8FEQ
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8FEP
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4TS9
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4TTJ
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 6 FMC molecules | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | Authors: | Stefanic, Z, Bzowska, A. | Deposit date: | 2014-06-21 | Release date: | 2015-07-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.874 Å) | Cite: | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
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4TTA
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 2 FMC molecules | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | Authors: | Stefanic, Z, Bzowska, A. | Deposit date: | 2014-06-20 | Release date: | 2015-07-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
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4TTI
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 4 FMC molecules | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | Authors: | Stefanic, Z, Bzowska, A. | Deposit date: | 2014-06-21 | Release date: | 2015-07-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
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8VAW
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8VAX
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