4RI2
 
 | | Crystal structure of the photoprotective protein PsbS from spinach | | Descriptor: | CHLOROPHYLL A, MERCURY (II) ION, Photosystem II 22 kDa protein, ... | | Authors: | Fan, M, Li, M, Chang, W. | | Deposit date: | 2014-10-05 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
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4RI3
 | | Crystal structure of DCCD-modified PsbS from spinach | | Descriptor: | DICYCLOHEXYLUREA, MERCURY (II) ION, Photosystem II 22 kDa protein, ... | | Authors: | Fan, M, Li, M, Chang, W. | | Deposit date: | 2014-10-05 | | Release date: | 2015-08-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
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6HK5
 | | X-ray structure of a truncated mutant of the metallochaperone CooJ with a high-affinity nickel-binding site | | Descriptor: | 3,3',3''-phosphoryltripropanoic acid, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Alfano, M, Perard, J, Basset, C, Carpentier, P, Zambelli, B, Timm, J, Crouzy, S, Ciurli, S, Cavazza, C. | | Deposit date: | 2018-09-05 | | Release date: | 2019-03-27 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.042 Å) | | Cite: | The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni(II)-binding site.
J.Biol.Chem., 294, 2019
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6C5W
 | | Crystal structure of the mitochondrial calcium uniporter | | Descriptor: | CALCIUM ION, calcium uniporter, nanobody | | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | | Deposit date: | 2018-01-17 | | Release date: | 2018-07-11 | | Last modified: | 2019-04-24 | | Method: | X-RAY DIFFRACTION (3.10010242 Å) | | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
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6C5R
 | | Crystal structure of the soluble domain of the mitochondrial calcium uniporter | | Descriptor: | calcium uniporter | | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | | Deposit date: | 2018-01-16 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.09608316 Å) | | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
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6WDO
 | | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | | Authors: | Feng, L, Zhang, J, Fan, M. | | Deposit date: | 2020-04-01 | | Release date: | 2020-05-27 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
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6WDN
 | | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+ | | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | | Authors: | Feng, L, Zhang, J, Fan, M. | | Deposit date: | 2020-04-01 | | Release date: | 2020-05-27 | | Last modified: | 2020-06-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
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8FHN
 | | Cryo-EM structure of human NCC (class 2) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHR
 | | Cryo-EM structure of human NCC (class 3-3) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHO
 | | Cryo-EM structure of human NCC (class 1) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, SODIUM ION, ... | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHP
 | | Cryo-EM structure of human NCC (class 3-1) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHT
 | | Cryo-EM structure of human NCC | | Descriptor: | CHLORIDE ION, SODIUM ION, Solute carrier family 12 member 3 | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-15 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHQ
 | | Cryo-EM structure of human NCC (class 3-2) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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5AEF
 | | Electron cryo-microscopy of an Abeta(1-42)amyloid fibril | | Descriptor: | AMYLOID BETA A4 PROTEIN | | Authors: | Schmidt, M, Rohou, A, Lasker, K, Yadav, J.K, Schiene-Fischer, C, Fandrich, M, Grigorieff, N. | | Deposit date: | 2015-08-29 | | Release date: | 2015-10-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em
Proc.Natl.Acad.Sci.USA, 112, 2015
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6MST
 | | Cryo-EM structure of human AA amyloid fibril | | Descriptor: | Serum amyloid A-1 protein | | Authors: | Loerch, S, Rennegarbe, M, Liberta, F, Grigorieff, N, Fandrich, M, Schmidt, M. | | Deposit date: | 2018-10-18 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
Nat Commun, 10, 2019
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7NSL
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1GXT
 | | Hydrogenase Maturation Protein HypF "acylphosphatase-like" N-terminal domain (HypF-ACP) in complex with Sulfate | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, HYDROGENASE MATURATION PROTEIN HYPF, ... | | Authors: | Rosano, C, Zuccotti, S, Stefani, M, Bucciantini, M, Ramponi, G, Bolognesi, M. | | Deposit date: | 2002-04-11 | | Release date: | 2002-09-12 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Crystal Structure and Anion Binding in the Prokaryotic Hydrogenase Maturation Factor Hypf Acylphosphatase-Like Domain
J.Mol.Biol., 321, 2002
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1GXU
 | | Hydrogenase Maturation Protein HypF "acylphosphatase-like" N-terminal domain (HypF-ACP) in complex with a substrate. Crystal grown in the presence of carbamoylphosphate | | Descriptor: | DIHYDROGENPHOSPHATE ION, HYDROGENASE MATURATION PROTEIN HYPF | | Authors: | Rosano, C, Zuccotti, S, Stefani, M, Bucciantini, M, Ramponi, G, Bolognesi, M. | | Deposit date: | 2002-04-11 | | Release date: | 2002-09-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Crystal Structure and Anion Binding in the Prokaryotic Hydrogenase Maturation Factor Hypf Acylphosphatase-Like Domain
J.Mol.Biol., 321, 2002
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6ZCG
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6DSO
 | | Cryo-EM structure of murine AA amyloid fibril | | Descriptor: | Serum amyloid A-2 protein | | Authors: | Loerch, S, Liberta, F, Grigorieff, N, Fandrich, M, Schmidt, M. | | Deposit date: | 2018-06-14 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
Nat Commun, 10, 2019
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6SHS
 | | Abeta fibril (Morphology I) | | Descriptor: | Amyloid-beta precursor protein | | Authors: | Kollmer, M, Fandrich, M. | | Deposit date: | 2019-08-08 | | Release date: | 2019-11-06 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM structure and polymorphism of A beta amyloid fibrils purified from Alzheimer's brain tissue.
Nat Commun, 10, 2019
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6Z1I
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6Z1O
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1OCE
 | | ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH MF268 | | Descriptor: | ACETYLCHOLINESTERASE, CIS-2,6-DIMETHYLMORPHOLINOOCTYLCARBAMYLESEROLINE | | Authors: | Bartolucci, C, Perola, E, Cellai, L, Brufani, M, Lamba, D. | | Deposit date: | 1998-06-12 | | Release date: | 1999-05-18 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | "Back door" opening implied by the crystal structure of a carbamoylated acetylcholinesterase.
Biochemistry, 38, 1999
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3TPK
 | | Crystal structure of the oligomer-specific KW1 antibody fragment | | Descriptor: | 1,2-ETHANEDIOL, BENZAMIDINE, Immunoglobulin heavy chain antibody variable domain KW1 | | Authors: | Parthier, C, Morgado, I, Stubbs, M.T, Fandrich, M. | | Deposit date: | 2011-09-08 | | Release date: | 2012-07-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment.
Proc.Natl.Acad.Sci.USA, 109, 2012
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