8F6R
 
 | | CryoEM structure of designed modular protein oligomer C6-79 | | Descriptor: | De novo designed oligomeric protein C6-79 | | Authors: | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | | Deposit date: | 2022-11-17 | | Release date: | 2023-11-29 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Cell, 187, 2024
|
|
8F6Q
 | | CryoEM structure of designed modular protein oligomer C8-71 | | Descriptor: | C8-71 | | Authors: | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | | Deposit date: | 2022-11-17 | | Release date: | 2023-11-29 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Cell, 187, 2024
|
|
8GEL
 | | Cryo-EM structure of synthetic tetrameric building block sC4 | | Descriptor: | sC4 | | Authors: | Redler, R.L, Huddy, T.F, Hsia, Y, Baker, D, Ekiert, D, Bhabha, G. | | Deposit date: | 2023-03-07 | | Release date: | 2024-03-13 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Blueprinting extendable nanomaterials with standardized protein blocks.
Nature, 627, 2024
|
|
7SEE
 | | Structure of E. coli LetB delta (Ring6) mutant, Ring1 in the closed state (Model 1) | | Descriptor: | MCE family protein, Intermembrane transport protein YebT chimera, UNKNOWN ATOM OR ION | | Authors: | Vieni, C, Coudray, N, Bhabha, G, Ekiert, D. | | Deposit date: | 2021-09-30 | | Release date: | 2022-02-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
|
|
7SEF
 | | Structure of E. coli LetB delta (Ring6) mutant, Ring 1 in the open state (Model 2, Rings 1-3 only) | | Descriptor: | MCE family protein, Intermembrane transport protein YebT chimera | | Authors: | Vieni, C, Coudray, N, Bhabha, G, Ekiert, D. | | Deposit date: | 2021-09-30 | | Release date: | 2022-02-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
|
|
6XSS
 | | CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 | | Descriptor: | C4_nat_HFuse-7900 | | Authors: | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | | Deposit date: | 2020-07-16 | | Release date: | 2020-12-23 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
|
|
7UDJ
 | | Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide | | Descriptor: | 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4 | | Authors: | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D. | | Deposit date: | 2022-03-20 | | Release date: | 2023-03-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
|
|
6WYT
 | |
6WYR
 | | Crystal structure of anti-Muscle Specific Kinase (MuSK) Fab, MuSK1A | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MuSK1A heavy chain, ... | | Authors: | Vieni, C, Ekiert, D. | | Deposit date: | 2020-05-13 | | Release date: | 2020-07-29 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis.
J.Exp.Med., 217, 2020
|
|
