6WYT

Crystal structure of anti-Muscle Specific Kinase (MuSK) Fab, MuSK1B

Summary for 6WYT

• Entry DOI: 10.2210/pdb6wyt/pdb
• Descriptor: MuSK1B heavy chain, MuSK1B light chain, GLYCEROL, ... (5 entities in total)
• Functional Keywords: human fab, anti-musk, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 46646.68

Authors

Vieni, C.,Ekiert, D. (deposition date: 2020-05-13, release date: 2020-07-29, Last modification date: 2023-10-18)

• Primary citation: Fichtner, M.L.,Vieni, C.,Redler, R.L.,Kolich, L.,Jiang, R.,Takata, K.,Stathopoulos, P.,Suarez, P.A.,Nowak, R.J.,Burden, S.J.,Ekiert, D.C.,O'Connor, K.C.; Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis.; J.Exp.Med., 217:-, 2020; PubMed: 32820331; DOI: 10.1084/jem.20200513

Experimental method

X-RAY DIFFRACTION (1.75 Å)