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PDB: 27 件
4O32
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BU of 4o32 by Molmil
Structure of a malarial protein
分子名称: CHLORIDE ION, Thioredoxin
著者Egea, P.F, Koehl, A, Peng, M, Cascio, D.
登録日2013-12-17
公開日2014-12-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex.
Biochem.Biophys.Res.Commun., 456, 2015
5VKZ
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BU of 5vkz by Molmil
Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies
分子名称: Mitochondrial distribution and morphology protein 12
著者Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D.
登録日2017-04-24
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies.
Biochem. Biophys. Res. Commun., 488, 2017
4XBI
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BU of 4xbi by Molmil
Structure Of A Malarial Protein Involved in Proteostasis
分子名称: ClpB protein, putative,Green fluorescent protein, SULFATE ION
著者Egea, P.F, Ah Young, A.P, Cascio, D.
登録日2014-12-17
公開日2015-07-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.013 Å)
主引用文献Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
1FBY
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BU of 1fby by Molmil
CRYSTAL STRUCTURE OF THE HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO 9-CIS RETINOIC ACID
分子名称: (9cis)-retinoic acid, RETINOIC ACID RECEPTOR RXR-ALPHA
著者Egea, P.F, Mitschler, A, Rochel, N, Ruff, M, Chambon, P, Moras, D.
登録日2000-07-17
公開日2000-07-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.
EMBO J., 19, 2000
4IOD
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BU of 4iod by Molmil
Preliminary structural investigations of a malarial protein secretion system.
分子名称: Malarial CLP B2 atpase/HSP101 protein, SULFATE ION
著者Egea, P.F.
登録日2013-01-07
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
4IRF
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BU of 4irf by Molmil
Preliminary structural investigations of a malarial protein secretion system
分子名称: MALARIAL CLPB2 ATPASE/HSP101 PROTEIN
著者Egea, P.F.
登録日2013-01-14
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
3KOU
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BU of 3kou by Molmil
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD38 molecule, ...
著者Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N.J, Kellenberger, E, Schuber, F.
登録日2009-11-13
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
1RJ9
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BU of 1rj9 by Molmil
Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Signal Recognition Protein, ...
著者Egea, P.F, Shan, S.O, Napetschnig, J, Savage, D.F, Walter, P, Stroud, R.M.
登録日2003-11-18
公開日2004-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate twinning activates the signal recognition particle and its receptor
Nature, 427, 2004
3MP7
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Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
分子名称: Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Egea, P.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2010-04-26
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes.
Proc.Natl.Acad.Sci.USA, 107, 2010
3P5S
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BU of 3p5s by Molmil
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD38 molecule, SULFATE ION, ...
著者Egea, P.F, Muller-Stauffler, H, Kohn, I, Cakou-Kefir, C, Stroud, R.M, Kellenberburger, E, Schuber, F.
登録日2010-10-10
公開日2011-10-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
1MZN
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BU of 1mzn by Molmil
CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE
分子名称: 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, RXR retinoid X receptor
著者Egea, P.F, Mitschler, A, Moras, D.
登録日2002-10-09
公開日2002-10-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Recognition of Agonist Ligands by RXRs
MOL.ENDOCRINOL., 16, 2002
1MVC
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BU of 1mvc by Molmil
Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide
分子名称: 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, RXR retinoid X receptor
著者Egea, P.F, Mitschler, A, Moras, D.
登録日2002-09-24
公開日2002-10-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Recognition of Agonist Ligands by RXRs
MOL.ENDOCRINOL., 16, 2002
1MV9
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BU of 1mv9 by Molmil
Crystal Structure of the human RXR alpha ligand binding domain bound to the eicosanoid DHA (Docosa Hexaenoic Acid) and a coactivator peptide
分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Nuclear receptor coactivator 2, RXR retinoid X receptor
著者Egea, P.F, Mitschler, A, Moras, D.
登録日2002-09-24
公開日2002-10-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Recognition of Agonist Ligands by RXRs
MOL.ENDOCRINOL., 16, 2002
3DLU
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BU of 3dlu by Molmil
Structures of SRP54 and SRP19, the two proteins assembling the ribonucleic core of the Signal Recognition Particle from the archaeon Pyrococcus furiosus.
分子名称: BROMIDE ION, MALONATE ION, Signal recognition particle 19 kDa protein
著者Egea, P.F, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-06-29
公開日2008-11-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus.
Plos One, 3, 2008
3DM9
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BU of 3dm9 by Molmil
Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Signal recognition particle receptor
著者Egea, P.F, Tsuruta, H, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-06-30
公開日2008-11-11
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus furiosus: Implications for the Targeting Step at the Membrane.
Plos One, 3, 2008
3DLV
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BU of 3dlv by Molmil
Structures of SRP54 and SRP19, the two proteins assembling the ribonucleic core of the Signal Recognition Particle from the archaeon Pyrococcus furiosus.
分子名称: Signal recognition particle 19 kDa protein
著者Egea, P.F, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-06-29
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus.
Plos One, 3, 2008
3DM5
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BU of 3dm5 by Molmil
Structures of SRP54 and SRP19, the two proteins assembling the ribonucleic core of the Signal Recognition Particle from the archaeon Pyrococcus furiosus.
分子名称: ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
著者Egea, P.F, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-06-30
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus.
Plos One, 3, 2008
3DMD
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BU of 3dmd by Molmil
Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus
分子名称: GLYCEROL, SULFATE ION, Signal recognition particle receptor
著者Egea, P.F, Tsuruta, H, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-06-30
公開日2008-11-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structures of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus furiosus: Implications for the Targeting Step at the Membrane.
Plos One, 3, 2008
3E70
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BU of 3e70 by Molmil
Structures and conformations in solution of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus Furiosus
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Signal recognition particle receptor
著者Egea, P.F, Tsuruta, H, Napetschnig, J, Walter, P, Stroud, R.M.
登録日2008-08-17
公開日2008-11-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane.
Plos One, 3, 2008
3GHH
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BU of 3ghh by Molmil
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION, ...
著者Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N.J, Kellenberger, E, Schuber, F.
登録日2009-03-03
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
3GC6
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BU of 3gc6 by Molmil
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION
著者Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N, Kellenberger, E, Schuber, F.
登録日2009-02-21
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
3GH3
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BU of 3gh3 by Molmil
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, Ecto-NAD+ glycohydrolase (CD38 molecule), ...
著者Egea, P.F, Muller-Steffner, H, Stroud, R.M, Kellenberger, E, Oppenheimer, N, Schuber, F.
登録日2009-03-02
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
4O2X
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BU of 4o2x by Molmil
Structure of a malarial protein
分子名称: Maltose-binding periplasmic protein, ATP-dependent Clp protease adaptor protein ClpS containing protein chimeric construct
著者AhYoung, A.P, Koehl, A, Cascio, D, Egea, P.F.
登録日2013-12-17
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum.
Protein Sci., 25, 2016
3BN9
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BU of 3bn9 by Molmil
Crystal Structure of MT-SP1 in complex with Fab Inhibitor E2
分子名称: 1,2-ETHANEDIOL, E2 Fab Heavy Chain, E2 Fab Light Chain, ...
著者Farady, C.J, Schneider, E.L, Egea, P.F, Goetz, D.H, Craik, C.S.
登録日2007-12-13
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition
J.Mol.Biol., 380, 2008
1RC2
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BU of 1rc2 by Molmil
2.5 Angstrom Resolution X-ray Structure of Aquaporin Z
分子名称: 2-O-octyl-beta-D-glucopyranose, Aquaporin Z
著者Savage, D.F, Egea, P.F, Robles, Y.C, O'Connell III, J.D, Stroud, R.M.
登録日2003-11-03
公開日2003-11-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z
Plos Biol., 1, 2003

 

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