4UWA
 
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3M9S
 | | Crystal structure of respiratory complex I from Thermus thermophilus | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | 著者 | Efremov, R.G, Baradaran, R, Sazanov, L.A. | | 登録日 | 2010-03-22 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The architecture of respiratory complex I
Nature, 465, 2010
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4UWE
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3M9C
 | | Crystal structure of the membrane domain of respiratory complex I from Escherichia coli | | 分子名称: | NADH-quinone oxidoreductase subunit NuoL, NADH-quinone oxidoreductase subunit NuoM, NADH-quinone oxidoreductase subunit NuoN, ... | | 著者 | Efremov, R.G, Baradaran, R, Sazanov, L.A. | | 登録日 | 2010-03-22 | | 公開日 | 2010-05-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | The architecture of respiratory complex I
Nature, 465, 2010
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3POU
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3POX
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3RKO
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3POQ
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8BYI
 | | Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in complex with CHAPS(Alpo4_CHAPS) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Acetylcholine receptor, ... | | 著者 | De Gieter, S, Efremov, R.G, Ulens, C. | | 登録日 | 2022-12-13 | | 公開日 | 2023-07-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
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8OQY
 | | Structure of apo form of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | | 登録日 | 2023-04-12 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform.
Nat Commun, 15, 2024
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8OQZ
 | | Structure of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc in complex with Ab46 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | | 登録日 | 2023-04-12 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform.
Nat Commun, 15, 2024
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5LUE
 | | Minor form of the recombinant cytotoxin-1 from N. oxiana | | 分子名称: | VC-1=CYTOTOXIN | | 著者 | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | 登録日 | 2016-09-08 | | 公開日 | 2017-09-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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5T8A
 | | Recombinant cytotoxin-I from the venom of cobra N. oxiana | | 分子名称: | Cytotoxin 1 | | 著者 | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | 登録日 | 2016-09-07 | | 公開日 | 2017-09-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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7QD8
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in apo state | | 分子名称: | Transposase for transposon Tn4430 | | 著者 | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | 登録日 | 2021-11-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD4
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 100 bp long transposon end DNA | | 分子名称: | IR100 DNA substrate, none transferred strand, transferred strand, ... | | 著者 | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | 登録日 | 2021-11-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD6
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with strand-transfer like DNA product | | 分子名称: | IR71st non transferred strand, IR71st transferred strand, Transposase for transposon Tn4430 | | 著者 | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | 登録日 | 2021-11-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD5
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 48 bp long transposon end DNA | | 分子名称: | IR48 DNA substrate, non transferred strand, IR48 transferred strand, ... | | 著者 | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | 登録日 | 2021-11-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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5NQ4
 | | Cytotoxin-1 in DPC-micelle | | 分子名称: | Cytotoxin 1 | | 著者 | Dubovskii, P.V, Dubinnyi, M.A, Volynsky, P.E, Pustovalova, Y.E, Konshina, A.G, Utkin, Y.N, Efremov, R.G, Arseniev, A.S. | | 登録日 | 2017-04-19 | | 公開日 | 2017-12-13 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Impact of membrane partitioning on the spatial structure of an S-type cobra cytotoxin.
J. Biomol. Struct. Dyn., 36, 2018
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1ZAD
 | | Structure of cytotoxin I (CTI) from Naja Oxiana in complex with DPC micelle | | 分子名称: | Cytotoxin 1 | | 著者 | Dubinnyi, M.A, Pustovalova, Y.E, Dubovskii, P.V, Utkin, Y.N, Konshina, A.G, Efremov, R.G, Arseniev, A.S. | | 登録日 | 2005-04-06 | | 公開日 | 2006-06-20 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Interaction of three-finger toxins with phospholipid membranes: comparison of S- and P-type cytotoxins
Biochem.J., 387, 2005
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1DXZ
 | | M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES | | 分子名称: | ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN | | 著者 | Pashkov, V.S, Maslennikov, I.V, Tchikin, L.D, Efremov, R.G, Ivanov, V.T, Arseniev, A.S. | | 登録日 | 2000-01-20 | | 公開日 | 2000-02-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Spatial Structure of the M2 Transmembrane Segment of the Nicotinic Acetylcholine Receptor Alpha-Subunit
FEBS Lett., 457, 1999
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6FG3
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6FOO
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2G9P
 | | NMR structure of a novel antimicrobial peptide, latarcin 2a, from spider (Lachesana tarabaevi) venom | | 分子名称: | antimicrobial peptide Latarcin 2a | | 著者 | Dubovskii, P.V, Volynsky, P.E, Polyansky, A.A, Chupin, V.V, Efremov, R.G, Arseniev, A.S. | | 登録日 | 2006-03-07 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Spatial structure and activity mechanism of a novel spider antimicrobial peptide.
Biochemistry, 45, 2006
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4O9Y
 | | Crystal Structure of TcdA1 | | 分子名称: | TcdA1 | | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | 登録日 | 2014-01-03 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
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4O9X
 | | Crystal Structure of TcdB2-TccC3 | | 分子名称: | MERCURY (II) ION, TcdB2, TccC3 | | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | 登録日 | 2014-01-03 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
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