8R3Y
 
 | | Cryo EM structure of a stable LGL/aPKC Iota/Par-6 complex | | 分子名称: | Lethal(2) giant larvae protein homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Partitioning defective 6 homolog alpha, ... | | 著者 | Earl, C.P, Briggs, D.C, McDonald, N.Q. | | 登録日 | 2023-11-10 | | 公開日 | 2024-11-20 | | 最終更新日 | 2025-04-23 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.
Nat.Struct.Mol.Biol., 32, 2025
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7AB8
 | | Crystal structure of a GDNF-GFRalpha1 complex | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Adams, S.E, Earl, C.P, Purkiss, A.G, McDonald, N.Q. | | 登録日 | 2020-09-07 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
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8R3X
 | | Crystal structure of aPKC Iota kinase domain with LLGL2 peptide | | 分子名称: | LLGL scribble cell polarity complex component 2, Protein kinase C iota type | | 著者 | Soriano, E.V, Earl, C.P, Briggs, D.C, McDonald, N.Q. | | 登録日 | 2023-11-10 | | 公開日 | 2024-11-20 | | 最終更新日 | 2025-04-23 | | 実験手法 | X-RAY DIFFRACTION (2.591 Å) | | 主引用文献 | Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.
Nat.Struct.Mol.Biol., 32, 2025
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7AML
 | | RET/GDNF/GFRa1 extracellular complex Cryo-EM structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha, ... | | 著者 | Adams, S.E, Earl, C.P, Purkiss, A.G, McDonald, N.Q. | | 登録日 | 2020-10-09 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
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