2AK3
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8QMZ
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![BU of 8qmz by Molmil](/molmil-images/mine/8qmz) | Soluble epoxide hydrolase in complex with RK4 | Descriptor: | (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2 | Authors: | Kumar, A, Zhu, F, Ehrler, J.M.H, Li, F, Empel, C, Xu, Y, Atodiresei, I, Koenigs, R.M, Proschak, E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-09-25 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Photosensitization enables Pauson-Khand-type reactions with nitrenes. Science, 383, 2024
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4QVP
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![BU of 4qvp by Molmil](/molmil-images/mine/4qvp) | yCP beta5-M45T mutant in complex with bortezomib | Descriptor: | CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... | Authors: | Huber, E.M, Heinemeyer, W, Groll, M. | Deposit date: | 2014-07-15 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
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2AGG
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![BU of 2agg by Molmil](/molmil-images/mine/2agg) | succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution | Descriptor: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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4QWK
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![BU of 4qwk by Molmil](/molmil-images/mine/4qwk) | yCP beta5-A49T-A50V-double mutant in complex with carfilzomib | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Huber, E.M, Heinemeyer, W, Groll, M. | Deposit date: | 2014-07-16 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
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4XYG
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4ISM
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8QWT
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5K7O
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![BU of 5k7o by Molmil](/molmil-images/mine/5k7o) | MicroED structure of lysozyme at 1.8 A resolution | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | Deposit date: | 2016-05-26 | Release date: | 2017-04-05 | Last modified: | 2018-08-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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3OXQ
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![BU of 3oxq by Molmil](/molmil-images/mine/3oxq) | Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C | Authors: | Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2010-09-21 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29, 2010
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5CLX
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![BU of 5clx by Molmil](/molmil-images/mine/5clx) | X-ray structure of perdeuterated TTR mutant - S52P at 1.28A resolution | Descriptor: | GLYCEROL, Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | X-ray structure of perdeuterated TTR mutant - S52P at 1.28A resolution To Be Published
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1CBV
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![BU of 1cbv by Molmil](/molmil-images/mine/1cbv) | AN AUTOANTIBODY TO SINGLE-STRANDED DNA: COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF THE UNLIGANDED FAB AND A DEOXYNUCLEOTIDE-FAB COMPLEX | Descriptor: | DNA (5'-D(*TP*TP*T)-3'), PROTEIN (FAB (BV04-01) AUTOANTIBODY-HEAVY CHAIN), PROTEIN (FAB (BV04-01) AUTOANTIBODY-LIGHT CHAIN) | Authors: | Herron, J.N, He, X.M, Ballard, D.W, Blier, P.R, Pace, P.E, Bothwell, A.L.M, Voss Junior, E.W, Edmundson, A.B. | Deposit date: | 1993-03-16 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex. Proteins, 11, 1991
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8J9T
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![BU of 8j9t by Molmil](/molmil-images/mine/8j9t) | Crystal Structure of GyraseA N-terminal at 2.43A Resolution | Descriptor: | CARBONATE ION, DNA gyrase subunit A | Authors: | Salman, M, Sachdeva, E, Das, U, Singh, T.P, Ethayathullah, A.S, Kaur, P. | Deposit date: | 2023-05-04 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.428 Å) | Cite: | Crystal Structure of GyraseA N-terminal at 2.43A Resolution to be published
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3LIR
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![BU of 3lir by Molmil](/molmil-images/mine/3lir) | Human MMP12 in complex with non-zinc chelating inhibitor | Descriptor: | CALCIUM ION, GLYCINE, Macrophage metalloelastase, ... | Authors: | Stura, E.A, Dive, V, Devel, L, Czarny, B, Vera, L, Beau, F. | Deposit date: | 2010-01-25 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation. J.Biol.Chem., 285, 2010
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1C9D
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4QZ1
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![BU of 4qz1 by Molmil](/molmil-images/mine/4qz1) | yCP beta5-M45T mutant in complex with the epoxyketone inhibitor ONX 0914 | Descriptor: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Huber, E.M, Heinemeyer, W, Groll, M. | Deposit date: | 2014-07-27 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
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5CNB
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![BU of 5cnb by Molmil](/molmil-images/mine/5cnb) | Ultrafast dynamics in myoglobin: 0.5 ps time delay | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K.J, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M.C, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. | Deposit date: | 2015-07-17 | Release date: | 2015-09-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
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2AQT
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![BU of 2aqt by Molmil](/molmil-images/mine/2aqt) | CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant | Descriptor: | COPPER (I) ION, COPPER (II) ION, SULFATE ION, ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant To be Published
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6EDI
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8QWX
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![BU of 8qwx by Molmil](/molmil-images/mine/8qwx) | Ligninolytic manganese peroxidase Ape-MnP1 from Agaricales mushrooms | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Santillana, E, Romero, A. | Deposit date: | 2023-10-20 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-function characterization of two enzymes from novel subfamilies of manganese peroxidases secreted by the lignocellulose-degrading Agaricales fungi Agrocybe pediades and Cyathus striatus. Biotechnol Biofuels Bioprod, 17, 2024
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3OZW
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![BU of 3ozw by Molmil](/molmil-images/mine/3ozw) | The Crystal Structure of flavohemoglobin from R. eutrophus in complex with ketoconazole | Descriptor: | 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | El Hammi, E, Warkentin, E, Demmer, U, Ermler, U, Baciou, L. | Deposit date: | 2010-09-27 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds. Biochemistry, 50, 2011
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8QOY
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![BU of 8qoy by Molmil](/molmil-images/mine/8qoy) | Capsular polysaccharide synthesis multienzyme of Actinobacillus Pleuropneumoniae serotype 3 | Descriptor: | SULFATE ION, TagF-like capsule polymerase Cps3D, ZINC ION | Authors: | Di Domenico, V, Litschko, C, Schulze, J, Bethe, A, Cifuente, J.O, Marina, A, Budde, I, Mast, T.A, Sulewska, M, Berger, M, Buettner, F, Gerardy-Schahn, R, Fiebig, T, Guerin, M.E. | Deposit date: | 2023-09-29 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Transition transferases prime bacterial capsule polymerization. Nat.Chem.Biol., 2024
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8QZW
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7UOF
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![BU of 7uof by Molmil](/molmil-images/mine/7uof) | Dihydroorotase from M. jannaschii | Descriptor: | Dihydroorotase, ZINC ION | Authors: | Vitali, J, Nix, J.C, Newman, H.E, Colaneri, M.J. | Deposit date: | 2022-04-12 | Release date: | 2022-08-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Methanococcus jannaschii dihydroorotase. Proteins, 91, 2023
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8U4C
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![BU of 8u4c by Molmil](/molmil-images/mine/8u4c) | Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation. | Descriptor: | Insulin receptor, Insulin-like growth factor II | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2023-09-10 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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