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PDB: 40736 件

6WRO
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CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM BUT NO LITHIUM AT 3 ANGSTROM RESOLUTION
分子名称: GADOLINIUM ATOM, Inositol polyphosphate 1-phosphatase, SULFATE ION
著者Dollins, D.E, Endo-Streeter, S, York, J.D.
登録日2020-04-29
公開日2020-11-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structural basis for lithium and substrate binding of an inositide phosphatase.
J.Biol.Chem., 296, 2020
5M0R
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Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex
分子名称: integrase, tDNA, vDNA, ...
著者Pye, V.E, Ballandras-Colas, A, Maskell, D, Locke, J, Kotecha, A, Costa, A, Cherepanov, P.
登録日2016-10-05
公開日2017-01-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献A supramolecular assembly mediates lentiviral DNA integration.
Science, 355, 2017
7QUD
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D. melanogaster alpha/beta tubulin heterodimer in the GTP form
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin alpha-1 chain, ...
著者Wagstaff, J, Planelles-Herrero, V.J, Derivery, E, Lowe, J.
登録日2022-01-17
公開日2022-09-21
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics.
Sci Adv, 9, 2023
7N06
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SARS-CoV-2 Nsp15 endoribonuclease post-cleavage state
分子名称: RNA (5'-R(*AP*UP*A)-3'), Uridylate-specific endoribonuclease
著者Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E.
登録日2021-05-25
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Nucleic Acids Res., 49, 2021
7NP7
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Structure of an intact ESX-5 inner membrane complex, Composite C1 model
分子名称: ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ...
著者Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C.
登録日2021-02-26
公開日2021-06-02
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Structure and dynamics of a mycobacterial type VII secretion system.
Nature, 593, 2021
7NNH
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Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6
分子名称: Erythrocyte membrane protein 1
著者Wang, K.T, Dagil, R, Salanti, A, Gourdon, P.E.
登録日2021-02-24
公開日2021-06-02
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7Q0X
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Bovine Trypsin co-crystallized with V(IV)OSO4 and pic
分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
著者Santos, M.F.A, Fernandes, A.C.P, Correia, I, Sciortino, G, Garribba, E, Santos-Silva, T, Pessoa, J.C.
登録日2021-10-16
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X-ray/Theoretical Characterization and Biological Implications.
Chemistry, 28, 2022
7Q0U
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Lysozyme soaked with V(IV)OSO4 and bipy
分子名称: 2,2'-bipyridine, ACETATE ION, CHLORIDE ION, ...
著者Santos, M.F.A, Fernandes, A.C.P, Correia, I, Sciortino, G, Garribba, E, Santos-Silva, T, Pessoa, J.C.
登録日2021-10-16
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X-ray/Theoretical Characterization and Biological Implications.
Chemistry, 28, 2022
7Q0V
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Lysozyme soaked with V(IV)OSO4 and phen
分子名称: 1,10-PHENANTHROLINE, ACETATE ION, CHLORIDE ION, ...
著者Santos, M.F.A, Fernandes, A.C.P, Correia, I, Sciortino, G, Garribba, E, Santos-Silva, T, Pessoa, J.C.
登録日2021-10-16
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X-ray/Theoretical Characterization and Biological Implications.
Chemistry, 28, 2022
7NPR
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Structure of an intact ESX-5 inner membrane complex, Composite C3 model
分子名称: ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ...
著者Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C.
登録日2021-02-28
公開日2021-06-02
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure and dynamics of a mycobacterial type VII secretion system.
Nature, 593, 2021
5J1T
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TorsinAdeltaE-LULL1 complex, H. sapiens, bound to VHH-BS2
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Demircioglu, F.E, Schwartz, T.U.
登録日2016-03-29
公開日2016-08-17
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Elife, 5, 2016
6NID
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Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain in complex with Neurexin-1 peptide
分子名称: 1,2-ETHANEDIOL, Neurexin-1, Peripheral plasma membrane protein CASK
著者Sun, Y.J, Gakhar, L, Fuentes, E.J.
登録日2018-12-27
公開日2020-01-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献CASK PDZ domain specificity
To be published
7Q0W
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Bovine Trypsin co-crystallized with V(IV)OSO4 and phen
分子名称: 1,10-PHENANTHROLINE, CALCIUM ION, Cationic trypsin, ...
著者Santos, M.F.A, Fernandes, A.C.P, Correia, I, Sciortino, G, Garribba, E, Santos-Silva, T, Pessoa, J.C.
登録日2021-10-16
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X-ray/Theoretical Characterization and Biological Implications.
Chemistry, 28, 2022
6NJM
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Architecture and subunit arrangement of native AMPA receptors
分子名称: 15F1 Fab heavy chain, 15F1 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
5MBU
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CeuE (H227A, Y288F variant) a periplasmic protein from Campylobacter jejuni
分子名称: Enterochelin uptake periplasmic binding protein
著者Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S.
登録日2016-11-08
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
7ZHJ
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Tail tip of siphophage T5 : tip proteins
分子名称: Distal tail protein, L-shaped tail fiber protein p132, Minor tail protein, ...
著者Linares, R, Arnaud, C.A, Effantin, G, Darnault, C, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C.
登録日2022-04-06
公開日2023-02-08
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation.
Sci Adv, 9, 2023
6YE9
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Small-molecule inhibitor of 14-3-3 protein-protein interactions
分子名称: 14-3-3 protein sigma, MAGNESIUM ION, [2-[2-oxidanylidene-2-[(phenylmethyl)amino]ethoxy]phenyl]phosphonic acid
著者Ottmann, C, Visser, E.J.
登録日2020-03-24
公開日2021-03-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based conversion of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions
To Be Published
7N33
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BU of 7n33 by Molmil
SARS-CoV-2 Nsp15 endoribonuclease pre-cleavage state
分子名称: RNA (5'-R(*A)-D(*(UFT))-R(P*A)-3'), Uridylate-specific endoribonuclease
著者Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E.
登録日2021-05-31
公開日2021-06-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Nucleic Acids Res., 49, 2021
7ZN4
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Tail tip of siphophage T5 : bent fibre after interaction with its bacterial receptor FhuA
分子名称: Probable baseplate hub protein, Probable central straight fiber
著者Linares, R, Arnaud, C.A, Effantin, G, Darnault, C, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C.
登録日2022-04-20
公開日2023-02-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.32 Å)
主引用文献Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation.
Sci Adv, 9, 2023
7ZQB
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Tail tip of siphophage T5 : full structure
分子名称: Distal tail protein, L-shaped tail fiber protein p132, Minor tail protein, ...
著者Linares, R, Arnaud, C.A, Effantin, G, Darnault, C, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C.
登録日2022-04-29
公開日2023-02-08
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation.
Sci Adv, 9, 2023
7C07
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Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA.
分子名称: RNA (5'-R(*U*AP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2020-04-30
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
5MC6
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Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
登録日2016-11-09
公開日2017-01-18
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
5MI0
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A thermally stabilised version of Plasmodium falciparum RH5
分子名称: MONOCLONAL ANTIBODY 9AD4, Reticulocyte binding-like protein 5,Reticulocyte binding protein 5
著者Campeotto, I, Goldenzweig, A, Davey, J, Barfod, L, Marshall, J.M, Silk, S.E, Wright, K.E, Draper, S.J, Higgins, M.K, Fleishman, S.J.
登録日2016-11-27
公開日2016-12-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4WTD
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CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH ADP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AUAAAUUU
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MANGANESE (II) ION, ...
著者Edwards, T.E, Fox III, D, Appleby, T.C.
登録日2014-10-29
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for RNA replication by the hepatitis C virus polymerase.
Science, 347, 2015
6NOS
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PD-L1 IgV domain V76T with fragment
分子名称: 1-[5-(3,5-dichlorophenyl)furan-2-yl]-N-methylmethanamine, Programmed cell death 1 ligand 1
著者Zhao, B, Perry, E.
登録日2019-01-16
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019

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