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PDB: 11 件

6IQ4
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Nucleosome core particle cross-linked with a hetero-binuclear molecule possessing RAPTA and gold(I) 4-(diphenylphosphino)benzoic acid groups.
分子名称: 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ...
著者DeFalco, L, Batchelor, L.K, Adhireksan, Z, Dyson, P.J, Davey, C.A.
登録日2018-11-06
公開日2019-10-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crosslinking Allosteric Sites on the Nucleosome.
Angew.Chem.Int.Ed.Engl., 58, 2019
5XF6
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker
分子名称: DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF4
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration)
分子名称: (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF3
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF5
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration)
分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
4AUT
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Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis
分子名称: DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C.
登録日2012-05-21
公開日2012-09-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis.
Sci. Transl. Med., 4, 2012
8Q3E
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High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide
分子名称: DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q3M
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Structure of Nucleosome Core with a Bound Kaposi Sarcoma Associated Herpesvirus LANA Peptide Having a Methionine to Ornithine Substitution
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q36
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Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Foamy Virus GAG Peptide-Au[I] Compound)
分子名称: DNA (145-MER), GAG structural protein, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q3X
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Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Kaposi Sarcoma Associated Herpesvirus LANA Peptide-Au[I] Compound)
分子名称: 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
5CP6
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Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
分子名称: (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2015-07-21
公開日2016-06-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55, 2016

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件を2024-10-30に公開中

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