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PDB: 88 件

6NY6
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Structure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
登録日2019-02-11
公開日2019-08-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.74 Å)
主引用文献Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
登録日2019-01-24
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.397 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NDK
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BU of 6ndk by Molmil
Structure of ASLSufA6 A37.5 bound to the 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.T, Hoffer, E.D, Dunham, C.M.
登録日2018-12-13
公開日2019-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing intRNACGGProfor decoding
J. Biol. Chem., 294, 2019
6NWY
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BU of 6nwy by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-07
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NUO
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BU of 6nuo by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-01
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-26
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6OPE
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BU of 6ope by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-24
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OF6
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BU of 6of6 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-03-28
公開日2020-06-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
4YZV
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BU of 4yzv by Molmil
Precleavage 70S structure of the P. vulgaris HigB deltaH92 toxin bound to the ACA codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-25
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZSN
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BU of 4zsn by Molmil
70S-wild-type HigB toxin complex bound to a AAA lysine codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunham, C.M.
登録日2015-05-13
公開日2016-09-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism of endonuclease cleavage by the HigB toxin.
Nucleic Acids Res., 44, 2016
4YPB
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BU of 4ypb by Molmil
Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-12
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YY3
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BU of 4yy3 by Molmil
30S ribosomal subunit- HigB complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Schureck, M.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-23
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献mRNA bound to the 30S subunit is a HigB toxin substrate.
Rna, 22, 2016
4OX9
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BU of 4ox9 by Molmil
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
分子名称: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Conn, G.L, Dunham, C.M.
登録日2014-02-04
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.8035 Å)
主引用文献Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P70
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BU of 4p70 by Molmil
Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2014-03-25
公開日2014-08-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.68 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P6F
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BU of 4p6f by Molmil
Crystal structure of the peptolide 12C bound to bacterial ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunham, C.M.
登録日2014-03-24
公開日2014-10-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome.
Acs Chem.Biol., 9, 2014
4PX8
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BU of 4px8 by Molmil
Structure of P. vulgaris HigB toxin
分子名称: CHLORIDE ION, Killer protein
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2014-03-22
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Q2U
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BU of 4q2u by Molmil
Crystal structure of the E. coli DinJ-YafQ toxin-antitoxin complex
分子名称: Antitoxin DinJ, SULFATE ION, mRNA interferase YafQ
著者Maehigashi, T, Ruangprasert, A, Dunham, C.M.
登録日2014-04-09
公開日2014-06-11
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanisms of Toxin Inhibition and Transcriptional Repression by Escherichia coli DinJ-YafQ.
J.Biol.Chem., 289, 2014
5UCT
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BU of 5uct by Molmil
Mycobacterium tuberculosis toxin MazF-mt6
分子名称: Endoribonuclease MazF3, SULFATE ION
著者Hoffer, E.H, Dunham, C.M.
登録日2016-12-22
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases.
J. Biol. Chem., 292, 2017
5VPP
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BU of 5vpp by Molmil
The 70S P-site tRNA SufA6 complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2017-05-05
公開日2018-09-26
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VPO
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BU of 5vpo by Molmil
The 70S P-site ASL SufA6 complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2017-05-05
公開日2018-09-26
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5UQ7
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BU of 5uq7 by Molmil
70S ribosome complex with dnaX mRNA stemloop and E-site tRNA ("in" conformation)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
登録日2017-02-07
公開日2018-03-07
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018
5UQ8
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BU of 5uq8 by Molmil
70S ribosome complex with dnaX mRNA stem-loop and E-site tRNA ("out" conformation)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
登録日2017-02-07
公開日2018-03-07
最終更新日2018-03-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018
4L71
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BU of 4l71 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-13
公開日2014-08-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.900001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4L47
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BU of 4l47 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-07
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.220001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LFZ
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BU of 4lfz by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of Paromomycin
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-27
公開日2014-08-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.92000055 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014

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