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PDB: 22 件
3MV1
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E.Coli (lacZ) beta-galactosidase (R599A) in complex with Guanidinium
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, GUANIDINE, ...
著者Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E.
登録日2010-05-03
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop
Biochem.Cell Biol., 88, 2010
3MUY
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E. coli (lacZ) beta-galactosidase (R599A)
分子名称: Beta-D-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E.
登録日2010-05-03
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Importance of Arg-599 of beta-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop
Biochem.Cell Biol., 88, 2010
3MV0
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E. COLI (lacZ) BETA-GALACTOSIDASE (R599A) IN COMPLEX WITH D-GALCTOPYRANOSYL-1-ONE
分子名称: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
著者Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E.
登録日2010-05-03
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop
Biochem.Cell Biol., 88, 2010
3MUZ
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BU of 3muz by Molmil
E.Coli (lacZ) beta-galactosidase (R599A) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Dugdale, M.L, Vance, M.L, Driedger, M.R, Nibber, A, Tran, A, Huber, R.E.
登録日2010-05-03
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop
Biochem.Cell Biol., 88, 2010
3I3D
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BU of 3i3d by Molmil
E. COLI (lacZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E.
登録日2009-06-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli).
Biochem.Cell Biol., 88, 2010
3I3E
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E. COLI (lacZ) BETA-GALACTOSIDASE (M542A)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E.
登録日2009-06-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli).
Biochem.Cell Biol., 88, 2010
3I3B
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BU of 3i3b by Molmil
E.coli (lacz) Beta-Galactosidase (M542A) in Complex with D-Galactopyranosyl-1-on
分子名称: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
著者Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E.
登録日2009-06-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli).
Biochem.Cell Biol., 88, 2010
4DUW
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E. coli (lacZ) beta-galactosidase (G974A) in complex with allolactose
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E.
登録日2012-02-22
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Explanation for Allolactose (lac operon inducer) Synthesis by lacZ beta-Galactosidase and the Evolutionary Relationship between Allolactose synthesis and the lac Repressor
J.Biol.Chem., 288, 2013
4DUV
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E. coli (lacZ) beta-galactosidase (G974A) 2-deoxy-galactosyl-enzyme and bis-Tris complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, ...
著者Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E.
登録日2012-02-22
公開日2013-04-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Glucose Acceptor site of lacZ beta-galactosidase for the synthesis of allolactose - the natural inducer of the lac operon
To be Published
4DUX
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E. coli (lacZ) beta-galactosidase (N460S) in complex with L-ribose
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E.
登録日2012-02-22
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural explanation for allolactose (lac operon inducer) synthesis by lacZ beta-galactosidase and the evolutionary relationship between allolactose synthesis and the lac repressor.
J.Biol.Chem., 288, 2013
3IAP
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BU of 3iap by Molmil
E. coli (lacZ) beta-galactosidase (E416Q)
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E.
登録日2009-07-14
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry
Protein J., 29, 2010
3IAQ
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E. coli (lacz) beta-galactosidase (E416V)
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E.
登録日2009-07-14
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry
Protein J., 29, 2010
3VD9
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BU of 3vd9 by Molmil
E. coli (lacZ) beta-galactosidase (N460S) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VDC
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BU of 3vdc by Molmil
E. coli (lacZ) beta-galactosidase (N460T) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD3
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BU of 3vd3 by Molmil
E. coli (lacZ) beta-galactosidase (N460D)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VDB
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E. coli (lacZ) beta-galactosidase (N460T) in complex with galactonolactone
分子名称: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD7
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E. coli (lacZ) beta-galactosidase (N460S) in complex with galactotetrazole
分子名称: (5R, 6S, 7S, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VDA
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BU of 3vda by Molmil
E. coli (lacZ) beta-galactosidase (N460T)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD5
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BU of 3vd5 by Molmil
E. coli (lacZ) beta-galactosidase (N460S)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD4
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BU of 3vd4 by Molmil
E. coli (lacZ) beta-galactosidase (N460D) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3CZJ
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BU of 3czj by Molmil
E. COLI (lacZ) BETA-GALACTOSIDASE (N460T) IN COMPLEX WITH D-GALCTOPYRANOSYL-1-ONE
分子名称: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
著者Huber, R.E, Dugdale, M.L, Fraser, M.E, Tammam, S.D.
登録日2008-04-29
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Practical Considerations When Using Temperature to Obtain Rate Constants and Activation Thermodynamics of Enzymes with Two Catalytic Steps: Native and N460T-beta-Galactosidase (E. coli) as Examples.
Protein J., 28, 2009
3E1F
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E.Coli (lacZ) beta-galactosidase (H418E) in complex with galactose
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Huber, R.E, Dugdale, M.L.
登録日2008-08-04
公開日2009-06-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein Sci., 18, 2009

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件を2024-05-15に公開中

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