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PDB: 6 件

5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
著者Doyle, C, Birrane, G.
登録日2015-08-17
公開日2016-01-13
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
5C0N
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BU of 5c0n by Molmil
Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease
分子名称: Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ...
著者Doyle, C.
登録日2015-06-12
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
4DG6
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BU of 4dg6 by Molmil
Crystal structure of domains 1 and 2 of LRP6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Low-density lipoprotein receptor-related protein 6, PHOSPHATE ION
著者Ceska, T.A, Doyle, C, Slocombe, P.
登録日2012-01-25
公開日2012-06-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Characterization of the interaction of sclerostin with the LRP family of Wnt co-receptors
To be Published
1OEC
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BU of 1oec by Molmil
FGFr2 kinase domain
分子名称: 4-ARYL-2-PHENYLAMINO PYRIMIDINE, FIBROBLAST GROWTH FACTOR RECEPTOR 2, SULFATE ION
著者Ceska, T.A, Owens, R, Doyle, C, Hamlyn, P, Crabbe, T, Moffat, D, Davis, J, Martin, R, Perry, M.J.
登録日2003-03-24
公開日2004-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of the Fgfr2 Tyrosine Kinase Domain in Complex with 4-Aryl-2-Phenylamino Pyrimidine Angiogenesis Inhibitors
To be Published
1GJO
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BU of 1gjo by Molmil
The FGFr2 tyrosine kinase domain
分子名称: FIBROBLAST GROWTH FACTOR RECEPTOR 2, SULFATE ION
著者Ceska, T.A, Owens, R, Doyle, C, Hamlyn, P, Crabbe, T, Moffat, D, Davis, J, Martin, R, Perry, M.J.
登録日2001-07-31
公開日2003-08-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Fgfr2 Tyrosine Kinase Domain
To be Published
5FUC
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BU of 5fuc by Molmil
Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-6, INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, ...
著者Adams, R, Griffin, R, Doyle, C, Ettorre, A.
登録日2016-01-25
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.
Sci Rep, 7, 2017

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件を2024-10-30に公開中

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